PMID- 19110528 OWN - NLM STAT- MEDLINE DCOM- 20090630 LR - 20191111 IS - 1349-533X (Electronic) IS - 1341-0725 (Linking) VI - 51 IP - 1 DP - 2009 Jan TI - [New investigation of the effect of toner and its by-products on human health and occupational health management of toner]. PG - 1-10 AB - We need a new investigation of the effect of not only toner but also of its by-products on human health, because of the generation of fine particles and the release of volatile organic compounds (VOC) in the process of photocopy. Therefore, we gathered epidemiological and animal data on toner and its by-products, and examined the occupational health management of toner. We examined the effect of carbonblack as the main component of toner, and titanium dioxide and amorphous silica as surface-adhesive nanomaterials, and VOC on human health, and reviewed them. We summarize the results as follows. 1) High sensitive c-reactive protein in serum, 8-hydroxydeoxyguanosine in urine, and heart rate variability (HRV) are useful for biological monitoring of exposure to toner and its by-products. 2) Particle number concentrations have been often measured by scanning mobility particle sizer (SMPS) compared with other apparatus, although this is not measurement gold standard. Taken together, we have examined whole occupational health management of toner and its by-products. FAU - Morimoto, Yasuo AU - Morimoto Y AD - Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Fukuoka, Japan. yasuom@med.uoeh-u.ac.jp FAU - Kitamura, Hiroko AU - Kitamura H FAU - Kuga, Hiroaki AU - Kuga H FAU - Ide, Reiko AU - Ide R FAU - Myojo, Toshihiko AU - Myojo T FAU - Higashi, Toshiaki AU - Higashi T FAU - Satoh, Toshihiko AU - Satoh T FAU - Aizawa, Yoshiharu AU - Aizawa Y LA - jpn PT - English Abstract PT - Journal Article PT - Review DEP - 20081225 PL - Japan TA - Sangyo Eiseigaku Zasshi JT - Sangyo eiseigaku zasshi = Journal of occupational health JID - 9507473 RN - 0 (Soot) RN - 0 (Volatile Organic Compounds) RN - 15FIX9V2JP (titanium dioxide) RN - 7631-86-9 (Silicon Dioxide) RN - D1JT611TNE (Titanium) SB - IM MH - Animals MH - *Copying Processes MH - *Environmental Monitoring MH - Humans MH - Nanoparticles MH - Occupational Health MH - Silicon Dioxide/toxicity MH - Soot/*toxicity MH - Titanium/toxicity MH - Volatile Organic Compounds/toxicity RF - 52 EDAT- 2008/12/27 09:00 MHDA- 2009/07/01 09:00 CRDT- 2008/12/27 09:00 PHST- 2008/12/27 09:00 [entrez] PHST- 2008/12/27 09:00 [pubmed] PHST- 2009/07/01 09:00 [medline] AID - JST.JSTAGE/sangyoeisei/A8001 [pii] AID - 10.1539/sangyoeisei.a8001 [doi] PST - ppublish SO - Sangyo Eiseigaku Zasshi. 2009 Jan;51(1):1-10. doi: 10.1539/sangyoeisei.a8001. Epub 2008 Dec 25.