PMID- 19112157
OWN - NLM
STAT- MEDLINE
DCOM- 20090415
LR  - 20130926
IS  - 8750-7587 (Print)
IS  - 0161-7567 (Linking)
VI  - 106
IP  - 3
DP  - 2009 Mar
TI  - Influence of acute exercise with and without carbohydrate replacement on 
      postprandial lipid metabolism.
PG  - 943-9
LID - 10.1152/japplphysiol.91367.2008 [doi]
AB  - Acute exercise, undertaken on the day before an oral fat tolerance test (OFTT), 
      typically reduces postprandial triglycerides (TG) and increases high-density 
      lipoprotein-cholesterol (HDL-C). However, the benefits of acute exercise may be 
      overstated when studies do not account for compensatory changes in dietary 
      intake. The objective of this study was to determine the influence of acute 
      exercise, with and without carbohydrate (CHO) replacement, on postprandial lipid 
      metabolism. Eight recreationally active young men underwent an OFTT on the 
      morning after three experimental conditions: no exercise [control (Con)], 
      prolonged exercise without CHO replacement (Ex-Def) and prolonged exercise with 
      CHO replacement to restore CHO and energy balance (Ex-Bal). The exercise session 
      in Ex-Def and Ex-Bal consisted of 90 min cycle ergometry at 70% peak oxygen 
      uptake (Vo(2peak)) followed by 10 maximal 1-min sprints. CHO replacement was 
      achieved using glucose solutions consumed at 0, 2, and 4 h postexercise. Muscle 
      glycogen was 40 +/- 4% (P < 0.05) and 94 +/- 3% (P = 0.24) of Con values on the 
      morning of the Ex-Def and Ex-Bal OFTT, respectively. Postprandial TG were 40 +/- 
      14% lower and postprandial HDL-C, free fatty acids, and 3-hydroxybutyrate were 
      higher in Ex-Def compared with Con (P < 0.05). Most importantly, these exercise 
      effects were not evident in Ex-Bal. Postprandial insulin and glucose and the 
      homeostatic model assessment of insulin resistance (HOMA(IR)) were not 
      significantly different across trials. There was no relation between the changes 
      in postprandial TG and muscle glycogen across trials. In conclusion, the 
      influence of acute exhaustive exercise on postprandial lipid metabolism is 
      largely dependent on the associated CHO and energy deficit.
FAU - Harrison, Michael
AU  - Harrison M
AD  - Department of Health, Sport and Exercise Science, Waterford Institute of 
      Technology, Waterford, Ireland. mharrison@wit.ie
FAU - O'Gorman, Donal J
AU  - O'Gorman DJ
FAU - McCaffrey, Noel
AU  - McCaffrey N
FAU - Hamilton, Marc T
AU  - Hamilton MT
FAU - Zderic, Theodore W
AU  - Zderic TW
FAU - Carson, Brian P
AU  - Carson BP
FAU - Moyna, Niall M
AU  - Moyna NM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20081226
PL  - United States
TA  - J Appl Physiol (1985)
JT  - Journal of applied physiology (Bethesda, Md. : 1985)
JID - 8502536
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Insulin)
RN  - 0 (Triglycerides)
RN  - 9005-79-2 (Glycogen)
SB  - IM
MH  - Administration, Oral
MH  - Dietary Carbohydrates/administration & dosage/*metabolism
MH  - Energy Metabolism
MH  - Exercise/*physiology
MH  - *Exercise Test
MH  - Food Deprivation/physiology
MH  - Glucose Tolerance Test
MH  - Glycogen/analysis
MH  - Hemodynamics
MH  - Humans
MH  - Hypertriglyceridemia/*blood
MH  - Insulin/blood
MH  - Insulin Resistance/physiology
MH  - Male
MH  - Muscle, Skeletal/chemistry
MH  - Oxygen Consumption
MH  - Postprandial Period/*physiology
MH  - Pulmonary Gas Exchange
MH  - Triglycerides/blood
EDAT- 2008/12/30 09:00
MHDA- 2009/04/16 09:00
CRDT- 2008/12/30 09:00
PHST- 2008/12/30 09:00 [entrez]
PHST- 2008/12/30 09:00 [pubmed]
PHST- 2009/04/16 09:00 [medline]
AID - 91367.2008 [pii]
AID - 10.1152/japplphysiol.91367.2008 [doi]
PST - ppublish
SO  - J Appl Physiol (1985). 2009 Mar;106(3):943-9. doi: 
      10.1152/japplphysiol.91367.2008. Epub 2008 Dec 26.