PMID- 19117817 OWN - NLM STAT- MEDLINE DCOM- 20090529 LR - 20091119 IS - 1878-7568 (Electronic) IS - 1742-7061 (Linking) VI - 5 IP - 4 DP - 2009 May TI - High-density polyethylene facial implants show surface oxidation in SEM and EDX examination: a pilot study. PG - 1158-62 LID - 10.1016/j.actbio.2008.11.027 [doi] AB - Previous histopathological studies on explanted Medpor high-density polyethylene (HDPE) facial implants indicated signs of material destruction and claimed to observe phagocytized HDPE particles within the tissue samples beside the usual type IV reaction with severe fibrosis. We examined new and explanted Medpor material with scanning electron microscopy (SEM) and energy-dispersive X-ray analysis (EDX). The implant surface of three patient-derived specimens showed significantly higher oxygenation in EDX analysis and morphological changes in SEM compared to the new unused material directly after opening of the package and after 1 year of exposure to air. Our preliminary findings indicate a possible oxidative biocorrosion in HDPE surgical implants. Further studies should confirm these pilot project results. FAU - Draenert, G F AU - Draenert GF AD - Clinic for Craniomaxillofacial Surgery, University of Mainz, Augustusplatz 2, 55131 Munich, Germany. draenert@yahoo.com FAU - Doeblinger, M AU - Doeblinger M FAU - Draenert, M AU - Draenert M FAU - Gosau, M AU - Gosau M LA - eng PT - Journal Article DEP - 20081210 PL - England TA - Acta Biomater JT - Acta biomaterialia JID - 101233144 RN - 9002-88-4 (Polyethylene) SB - IM MH - Chemistry Techniques, Analytical MH - Microscopy, Electron, Scanning MH - Oxidation-Reduction MH - Pilot Projects MH - Polyethylene/*chemistry MH - Prostheses and Implants/*ultrastructure MH - Surface Properties MH - *X-Rays EDAT- 2009/01/02 09:00 MHDA- 2009/05/30 09:00 CRDT- 2009/01/02 09:00 PHST- 2008/06/04 00:00 [received] PHST- 2008/11/15 00:00 [revised] PHST- 2008/11/19 00:00 [accepted] PHST- 2009/01/02 09:00 [entrez] PHST- 2009/01/02 09:00 [pubmed] PHST- 2009/05/30 09:00 [medline] AID - S1742-7061(08)00377-2 [pii] AID - 10.1016/j.actbio.2008.11.027 [doi] PST - ppublish SO - Acta Biomater. 2009 May;5(4):1158-62. doi: 10.1016/j.actbio.2008.11.027. Epub 2008 Dec 10.