PMID- 19126942
OWN - NLM
STAT- MEDLINE
DCOM- 20090331
LR  - 20161124
IS  - 0019-4832 (Print)
IS  - 0019-4832 (Linking)
VI  - 59
IP  - 4
DP  - 2007 Jul-Aug
TI  - Heparin induced thrombocytopenia management with bivalirudin.
PG  - 354-5
AB  - We report a case of Heparin Induced Thrombocytopenia (HIT) following percutaneous 
      coronary intervention. The case is unique in that thrombocytopenia occurred very 
      early after heparin administration and responded well to a regime of 
      bivalirudin-a direct thrombin inhibitor readily available in India. Heparin, 
      Thrombocytopenia, Bivalirudin Acute HIT, occurring within few hours of heparin 
      therapy have been reported in patients previously exposed to unfractionated 
      heparin (UFH) or low molecular weight heparin (LMWH) 1. Prompt recognition of the 
      condition and timely intervention with direct thrombin inhibitors, can result in 
      salvaging patients from this potentially fatal complication.
FAU - Meera, R
AU  - Meera R
AD  - Department of Cardiology, Kerala Institute of Medical Sciences, Trivandrum, 
      Kerala. meeradocpillai@yahoo.com
FAU - Rachel, D
AU  - Rachel D
FAU - Ramakrishnapillai, V
AU  - Ramakrishnapillai V
FAU - Vijayaraghavan, G
AU  - Vijayaraghavan G
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - India
TA  - Indian Heart J
JT  - Indian heart journal
JID - 0374675
RN  - 0 (Anticoagulants)
RN  - 0 (Hirudins)
RN  - 0 (Peptide Fragments)
RN  - 0 (Recombinant Proteins)
RN  - 9005-49-6 (Heparin)
RN  - TN9BEX005G (bivalirudin)
SB  - IM
CIN - Indian Heart J. 2007 Jul-Aug;59(4):297-8. PMID: 19126932
MH  - Anticoagulants/*adverse effects/*therapeutic use
MH  - Heparin/*adverse effects
MH  - Hirudins
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*therapy
MH  - Peptide Fragments/*therapeutic use
MH  - Recombinant Proteins/therapeutic use
MH  - Thrombocytopenia/*chemically induced
EDAT- 2007/07/01 00:00
MHDA- 2009/04/01 09:00
CRDT- 2009/01/08 09:00
PHST- 2009/01/08 09:00 [entrez]
PHST- 2007/07/01 00:00 [pubmed]
PHST- 2009/04/01 09:00 [medline]
PST - ppublish
SO  - Indian Heart J. 2007 Jul-Aug;59(4):354-5.