PMID- 19130961
OWN - NLM
STAT- MEDLINE
DCOM- 20090305
LR  - 20161124
IS  - 0194-5998 (Print)
IS  - 0194-5998 (Linking)
VI  - 140
IP  - 1
DP  - 2009 Jan
TI  - Old and new aspects of middle turbinate histopathology.
PG  - 48-54
LID - 10.1016/j.otohns.2008.10.006 [doi]
AB  - OBJECTIVE: To study the histology of the normal and pathologic middle turbinate 
      (MT). STUDY DESIGN: Nonrandomized, controlled study. SUBJECTS AND METHODS: 
      Qualitative and quantitative assessment of soft tissue and bony elements of 14 
      normal and 10 chronic rhinosinusitis (CRS) MT samples (patients' mean CT score, 
      6.5 +/- 6.7). A comparison with 14 normal inferior turbinate (IT) samples was 
      accomplished. Quantitative assessment was limited to the lateral mucosal layer 
      (LML). RESULTS: The thickness of the LML was significantly greater in pathologic 
      MT than in normal MT (P = 0.002). Except for veins that underwent significant 
      increase (P = 0.036), other soft tissue constituents of the pathologic MT did not 
      change significantly. Glands were more abundant in normal MT and veins in normal 
      IT (P < 0.001, P = 0.001, respectively). Qualitative assessment showed larger 
      veins in the normal IT compared with the normal MT. Inflammatory cell infiltrate, 
      edema, and fibrosis were found in CRS. None of our MT bones exhibited 
      osteomyelitic changes. CONCLUSIONS: The different proportion of glands suggests 
      varied functional roles for both the MT and IT. The significant involvement of 
      the MT in the inflammatory process of CRS and the relatively small size and 
      paucity of veins with relatively little effect on nasal airflow justify partial 
      excision of the MT.
FAU - Berger, Gilead
AU  - Berger G
AD  - Department of Otolaryngology-Head and Neck Surgery, Ear, Nose, and Throat 
      Histopathologic Research Laboratory, Meir Medical Center, Kfar Saba, Israel. 
      berger45@netvision.net.il
FAU - Finkelstein, Yehuda
AU  - Finkelstein Y
FAU - Ophir, Dov
AU  - Ophir D
FAU - Landsberg, Roee
AU  - Landsberg R
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - Otolaryngol Head Neck Surg
JT  - Otolaryngology--head and neck surgery : official journal of American Academy of 
      Otolaryngology-Head and Neck Surgery
JID - 8508176
SB  - IM
MH  - Adult
MH  - Aged
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Sinusitis/pathology
MH  - Tomography, X-Ray Computed
MH  - Turbinates/anatomy & histology/blood supply/diagnostic imaging/*pathology
EDAT- 2009/01/10 09:00
MHDA- 2009/03/06 09:00
CRDT- 2009/01/10 09:00
PHST- 2008/08/08 00:00 [received]
PHST- 2008/09/15 00:00 [revised]
PHST- 2008/10/01 00:00 [accepted]
PHST- 2009/01/10 09:00 [entrez]
PHST- 2009/01/10 09:00 [pubmed]
PHST- 2009/03/06 09:00 [medline]
AID - S0194-5998(08)01493-9 [pii]
AID - 10.1016/j.otohns.2008.10.006 [doi]
PST - ppublish
SO  - Otolaryngol Head Neck Surg. 2009 Jan;140(1):48-54. doi: 
      10.1016/j.otohns.2008.10.006.