PMID- 19136157
OWN - NLM
STAT- MEDLINE
DCOM- 20090609
LR  - 20090202
IS  - 1872-8464 (Electronic)
IS  - 0165-5876 (Linking)
VI  - 73
IP  - 3
DP  - 2009 Mar
TI  - Screening to detect permanent childhood hearing impairment in neonates 
      transferred from the newborn nursery.
PG  - 457-65
LID - 10.1016/j.ijporl.2008.12.001 [doi]
AB  - OBJECTIVES: The focus of this report is hearing screening of newborns transferred 
      from the regular nursery to a specialized area. The purpose of the study 
      undertaken was: (1) to determine whether screening coverage in this population 
      was achieved; (2) to establish whether the linkage between neonatal screening and 
      the diagnostic follow-up was carried out correctly; (3) to better determine the 
      incidence of permanent childhood hearing impairment (PCHI) in this at-risk 
      population. METHODS: Six population centres averaging 12,000 births annually 
      participated (Bordeaux, Lille, Paris, Marseille, Toulouse and Lyon). Automated 
      auditory brainstem response (AABR) (Natus ALGO 3i) screening was performed in two 
      stages: i.e. infants with initial "positive" results were screened a second time 
      using the same technique. Of the 117,103 babies born during the study period, 
      4972 neonates were "transferred" and comprised the population for this report 
      (4.2% of the total births). RESULTS AND DISCUSSION: Screening results for 4972 
      "transferred" neonates were compared with those of non-transferred neonates 
      (N=112,131). Screening coverage of eligible infants was significantly lower 
      (75.4%) in "transferred" neonates (3750 infants screened) compared to 97.5% 
      coverage of non-transferred neonates (109,349 infants screened). The rate of 
      positive results after the first stage AABR was higher in the "transferred" 
      population (11.1%) than in the non-transferred population (6.5%). Of the 415 
      "transferred" newborns with initial positive screens, 91.3% were rechecked as 
      stipulated in the project protocol. The second pre-discharge AABR ascertained 
      that in half of the cases auditory function had normalized in the day. Of the 183 
      "transferred" infants whose result remained suspect at the conclusion of both 
      stages of the neonatal screen (4.9% of the tested population), only 70.5% 
      returned to the audiology centre for diagnostic follow-up. The incidence of 
      bilateral PCHI was markedly higher (4/1000) in "transferred" infants than in the 
      non-transferred population (1.08/1000). CONCLUSIONS: The difficulty of obtaining 
      universal screening coverage in "transferred" infants was, unfortunately, 
      verified in this prospective, multicentre study. Further, the diversity of our 
      "transferred" population was not much greater than that revealed by careful 
      analysis of published hearing screening studies in neonatal intensive care unit 
      (NICU) infants. The influence of risk factors and their more or less complex 
      combinations is apparent.
FAU - Dauman, Rene
AU  - Dauman R
AD  - CHU de Bordeaux, Universite de Bordeaux, Service ORL, Unite medicale 
      d'Audiologie, 33076 Bordeaux, France. rene.dauman@chu-bordeaux.fr
FAU - Roussey, Michel
AU  - Roussey M
FAU - Belot, Veronique
AU  - Belot V
FAU - Denoyelle, Francoise
AU  - Denoyelle F
FAU - Roman, Stephane
AU  - Roman S
FAU - Gavilan-Cellie, Isabelle
AU  - Gavilan-Cellie I
FAU - Ruzza-Surroca, Isabelle
AU  - Ruzza-Surroca I
FAU - Calmels, Marie-Noelle
AU  - Calmels MN
FAU - Lina-Granade, Genevieve
AU  - Lina-Granade G
FAU - Houssin, Elise
AU  - Houssin E
FAU - Charlemagne, Agnes
AU  - Charlemagne A
FAU - Garabedian, Noel
AU  - Garabedian N
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20090110
PL  - Ireland
TA  - Int J Pediatr Otorhinolaryngol
JT  - International journal of pediatric otorhinolaryngology
JID - 8003603
SB  - IM
MH  - Evoked Potentials, Auditory, Brain Stem
MH  - Hearing Loss/congenital/*diagnosis
MH  - Humans
MH  - Infant, Newborn
MH  - Intensive Care Units, Neonatal
MH  - *Neonatal Screening
MH  - Nurseries, Hospital
MH  - Patient Discharge
EDAT- 2009/01/13 09:00
MHDA- 2009/06/10 09:00
CRDT- 2009/01/13 09:00
PHST- 2008/08/15 00:00 [received]
PHST- 2008/12/02 00:00 [revised]
PHST- 2008/12/02 00:00 [accepted]
PHST- 2009/01/13 09:00 [entrez]
PHST- 2009/01/13 09:00 [pubmed]
PHST- 2009/06/10 09:00 [medline]
AID - S0165-5876(08)00584-3 [pii]
AID - 10.1016/j.ijporl.2008.12.001 [doi]
PST - ppublish
SO  - Int J Pediatr Otorhinolaryngol. 2009 Mar;73(3):457-65. doi: 
      10.1016/j.ijporl.2008.12.001. Epub 2009 Jan 10.