PMID- 19137199 OWN - NLM STAT- MEDLINE DCOM- 20091110 LR - 20200413 IS - 1678-4782 (Electronic) IS - 0021-7557 (Linking) VI - 85 IP - 1 DP - 2009 Jan-Feb TI - Cognitive and behavioral status of low birth weight preterm children raised in a developing country at preschool age. PG - 35-41 LID - 10.2223/JPED.1859 [doi] AB - OBJECTIVE: To assess cognitive and behavioral development at preschool age of children born preterm and with low birth weight and raised in a developing country. METHODS: Prospective cross-sectional study of 80 neonates born in a university hospital in southern Brazil. Neuropsychological assessment at age 4-5 years included the Wechsler Preschool and Primary Scale of Intelligence (WPPSI), Conners' Parent Rating Scale-Revised, Denver test and neurological examination. Perinatal and early neuropsychomotor development information was collected from the database during follow-up. Results were related to birth weight, sex and gestational age. RESULTS: WPPSI scores were: total intelligence quotient (IQ) 88.00+/-16.96, verbal IQ 89.72+/-16.72, and executive IQ 88.12+/-15.71 for the group with less than 1,500 grams; and total IQ 91.11+/-14.73, verbal IQ 93.36+/-12.65, and executive IQ 90.20+/-16.06 for the group between 1,500 and 2,500 grams. The best scores were obtained in tests that evaluated capacity of abstraction and symbolization, picture completion and common perception, in which only 5% and 6.3% of the children had abnormal results, respectively. The lowest scores were obtained in tests that evaluated visual-motor coordination and flexibility-speed of reasoning, in which 27.5% and 16.3% of the children had abnormal results, respectively. A total of 32.5% had abnormal results in the arithmetic tests. Behaviors related to attention deficit/hyperactivity disorder (ADHD) were observed in 48% of the sample. Low score in the Bayley Mental Scale and abnormal result in the Denver test were significantly correlated to ADHD (p = 0.017 and p = 0.004). Abnormal results in the Bayley Mental Scale (p < 0.001), Denver test (p < 0.001) and neurological examination (p = 0.002) were associated with lower IQ. CONCLUSIONS: The results revealed an increased incidence of behavioral and cognitive disorders at preschool age. FAU - Espirito Santo, Julia L do AU - Espirito Santo JL AD - Divison of Neurology, Hospital Sao Lucas, Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil. FAU - Portuguez, Mirna W AU - Portuguez MW FAU - Nunes, Magda L AU - Nunes ML LA - eng LA - por PT - Journal Article DEP - 20090109 PL - Brazil TA - J Pediatr (Rio J) JT - Jornal de pediatria JID - 2985188R SB - IM MH - Attention Deficit Disorder with Hyperactivity/epidemiology MH - Brazil/epidemiology MH - Child MH - Child Behavior/*physiology MH - Child Development/*physiology MH - Child, Preschool MH - Cross-Sectional Studies MH - Female MH - Gestational Age MH - Humans MH - Infant, Low Birth Weight/*psychology MH - Infant, Newborn MH - Intelligence/*physiology MH - Male MH - Neuropsychological Tests MH - Premature Birth/*psychology MH - Prospective Studies EDAT- 2009/01/13 09:00 MHDA- 2009/11/11 06:00 CRDT- 2009/01/13 09:00 PHST- 2009/01/13 09:00 [entrez] PHST- 2009/01/13 09:00 [pubmed] PHST- 2009/11/11 06:00 [medline] AID - 10.2223/JPED.1859 [doi] PST - ppublish SO - J Pediatr (Rio J). 2009 Jan-Feb;85(1):35-41. doi: 10.2223/JPED.1859. Epub 2009 Jan 9.