PMID- 19139757 OWN - NLM STAT- MEDLINE DCOM- 20090708 LR - 20110606 IS - 1362-4393 (Print) IS - 1362-4393 (Linking) VI - 47 IP - 5 DP - 2009 May TI - Autonomic dysreflexia and associated acute neurogenic pulmonary edema in a patient with spinal cord injury: a case report and review of the literature. PG - 423-5 LID - 10.1038/sc.2008.152 [doi] AB - STUDY DESIGN: A case report of a patient with spinal cord injury with autonomic dysreflexia and associated acute neurogenic pulmonary edema. OBJECTIVE: To further describe autonomic dysreflexia as a potential cause of acute neurogenic pulmonary edema; specifically in a population with spinal cord injury. SETTING: James A Haley Veterans Hospital, Tampa, FL, USA. METHODS: A patient with a prior history of C5 AIS (ASIA impairment scale) B spinal cord injury was admitted for bowel preparation before a screening colonoscopy. During the 2-day bowel preparation, the patient developed severe autonomic dysreflexia. Due to persistent hypertension and acute onset respiratory failure, he required transfer to the intensive care setting. RESULTS: Following a complicated course, the patient expired without a definitive cause of death. Autopsy findings showed gross and microscopic evidence of pulmonary edema. CONCLUSIONS: To date, the association between autonomic dysreflexia and acute neurogenic pulmonary edema is not described in the spinal cord or rehabilitation literature. The purpose of this case report is to further describe the overlooked and/or under reported incidence of acute neurogenic pulmonary edema associated with episodes of dysreflexia in a population with spinal cord injury. FAU - Calder, K B AU - Calder KB AD - Department of Pathology, University of South Florida College of Medicine, Tampa, FL 33604, USA. kcalder@hsc.usf.edu FAU - Estores, I M AU - Estores IM FAU - Krassioukov, A AU - Krassioukov A LA - eng PT - Case Reports PT - Journal Article DEP - 20090113 PL - England TA - Spinal Cord JT - Spinal cord JID - 9609749 SB - IM MH - Autonomic Dysreflexia/*complications/etiology/*physiopathology MH - Autopsy MH - Fatal Outcome MH - Humans MH - Hypertension/etiology/physiopathology MH - Male MH - Middle Aged MH - Pulmonary Edema/*complications/etiology/pathology/physiopathology MH - Respiratory Insufficiency/etiology/physiopathology MH - Spinal Cord Injuries/*complications/pathology/*physiopathology EDAT- 2009/01/14 09:00 MHDA- 2009/07/09 09:00 CRDT- 2009/01/14 09:00 PHST- 2009/01/14 09:00 [entrez] PHST- 2009/01/14 09:00 [pubmed] PHST- 2009/07/09 09:00 [medline] AID - sc2008152 [pii] AID - 10.1038/sc.2008.152 [doi] PST - ppublish SO - Spinal Cord. 2009 May;47(5):423-5. doi: 10.1038/sc.2008.152. Epub 2009 Jan 13.