PMID- 19140832
OWN - NLM
STAT- MEDLINE
DCOM- 20090306
LR  - 20111117
IS  - 1399-0039 (Electronic)
IS  - 0001-2815 (Linking)
VI  - 73
IP  - 1
DP  - 2009 Jan
TI  - Polymorphisms of HLA genes in Western Javanese (Indonesia): close affinities to 
      Southeast Asian populations.
PG  - 46-53
LID - 10.1111/j.1399-0039.2008.01178.x [doi]
AB  - Identification of human leukocyte antigen (HLA) antigens that are known as the 
      highest polymorphic genes has become a valuable tool for tissue transplantation, 
      platelet transfusion, disease susceptibility or resistance, and forensic and 
      anthropological studies. In the present study, the allele and haplotype 
      frequencies of HLA-A, HLA-B, and HLA-DRB1 were studied in 237 unrelated healthy 
      Western Javanese (Indonesia) by the high-resolution polymerase chain 
      reaction-Luminex method. A total of 18 A, 40 B, and 20 DRB1 alleles were 
      identified. The most frequent HLA-A, -B, and -DRB1 alleles were HLA-A*2407 
      (21.6%), HLA-B*1502 (11.6%) and HLA-B*1513 (11.2%), and DRB1*1202 (37.8%), 
      respectively. The most frequent two-locus haplotypes were HLA-A*2407-B*3505 (7%) 
      and HLA-B*1513-DRB1*1202 (9.2%), and three-locus haplotypes were 
      HLA-A*3401-B*1521-DRB1*150201 (4.6%), HLA-A*2407-B*3505-DRB1*1202 (4.3%), and 
      HLA-A*330301-B*440302-DRB1*070101 (4.2%). HLA allele and haplotype frequencies in 
      addition to phylogenetic tree and principal component analyses based on the 
      four-digit sequence-level allele frequencies for HLA-A, HLA-B, and HLA-DRB1 
      showed that Western Javanese (Indonesia) was closest to Southeast Asian 
      populations.
FAU - Yuliwulandari, R
AU  - Yuliwulandari R
AD  - Department of Human Genetics, Graduate School of Medicine, University of Tokyo, 
      Tokyo, Japan.
FAU - Kashiwase, K
AU  - Kashiwase K
FAU - Nakajima, H
AU  - Nakajima H
FAU - Uddin, J
AU  - Uddin J
FAU - Susmiarsih, T P
AU  - Susmiarsih TP
FAU - Sofro, A S M
AU  - Sofro AS
FAU - Tokunaga, K
AU  - Tokunaga K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (HLA-A Antigens)
RN  - 0 (HLA-B Antigens)
RN  - 0 (HLA-DR Antigens)
RN  - 0 (HLA-DRB1 Chains)
RN  - 0 (HLA-DRB1*12:02 antigen)
SB  - IM
EIN - Tissue Antigens. 2009 Jun;73(6):632
MH  - Alleles
MH  - Asia, Southeastern
MH  - Gene Frequency/genetics
MH  - HLA-A Antigens/*genetics
MH  - HLA-B Antigens/*genetics
MH  - HLA-DR Antigens/*genetics
MH  - HLA-DRB1 Chains
MH  - Haplotypes/*genetics
MH  - Humans
MH  - Indonesia
MH  - *Phylogeny
MH  - *Polymorphism, Genetic
EDAT- 2009/01/15 09:00
MHDA- 2009/03/07 09:00
CRDT- 2009/01/15 09:00
PHST- 2009/01/15 09:00 [entrez]
PHST- 2009/01/15 09:00 [pubmed]
PHST- 2009/03/07 09:00 [medline]
AID - TAN1178 [pii]
AID - 10.1111/j.1399-0039.2008.01178.x [doi]
PST - ppublish
SO  - Tissue Antigens. 2009 Jan;73(1):46-53. doi: 10.1111/j.1399-0039.2008.01178.x.