PMID- 19140837 OWN - NLM STAT- MEDLINE DCOM- 20090306 LR - 20111117 IS - 1399-0039 (Electronic) IS - 0001-2815 (Linking) VI - 73 IP - 1 DP - 2009 Jan TI - Identification of a new HLA-B*40 allele, HLA-B*4081, in a Chinese individual. PG - 70-2 LID - 10.1111/j.1399-0039.2008.01171.x [doi] AB - A novel human leukocyte antigen (HLA)-B*40 allele, officially named B*4081, was identified during routine high-resolution sequence-based typing in a Chinese potential hematopoietic stem cell transplantation donor. The HLA-B*4081 allele shows one nucleotide difference from B*400101 in exon 2 at nucleotide position 124 where G-->C (codon 18 GGG-->CGG) resulting in a coding change, 18Gly is changed to Arg, this is a unique nucleotide change among the HLA class I alleles, suggesting a point mutation mechanism. FAU - Zou, H-Y AU - Zou HY AD - Immunogenetic Laboratory, Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong, China. FAU - Li, Z AU - Li Z FAU - Cheng, L-H AU - Cheng LH FAU - Wang, D-M AU - Wang DM FAU - Deng, Z-H AU - Deng ZH LA - eng SI - GENBANK/EU366958 PT - Journal Article PL - England TA - Tissue Antigens JT - Tissue antigens JID - 0331072 RN - 0 (HLA-B Antigens) RN - 0 (HLA-B*40:81 antigens) RN - 0 (HLA-B40 Antigen) SB - IM MH - Adult MH - *Alleles MH - Amino Acid Substitution/genetics MH - Base Sequence MH - China MH - Exons/genetics MH - HLA-B Antigens/*genetics MH - HLA-B40 Antigen MH - Hematopoietic Stem Cell Transplantation MH - Humans MH - Living Donors MH - Male MH - Molecular Sequence Data MH - Point Mutation/genetics MH - Sequence Alignment EDAT- 2009/01/15 09:00 MHDA- 2009/03/07 09:00 CRDT- 2009/01/15 09:00 PHST- 2009/01/15 09:00 [entrez] PHST- 2009/01/15 09:00 [pubmed] PHST- 2009/03/07 09:00 [medline] AID - TAN1171 [pii] AID - 10.1111/j.1399-0039.2008.01171.x [doi] PST - ppublish SO - Tissue Antigens. 2009 Jan;73(1):70-2. doi: 10.1111/j.1399-0039.2008.01171.x.