PMID- 19144238 OWN - NLM STAT- MEDLINE DCOM- 20091109 LR - 20191210 IS - 1475-2727 (Electronic) IS - 1368-9800 (Linking) VI - 12 IP - 9 DP - 2009 Sep TI - Evaluation of relative intake of fatty acids according to the Northern Sweden FFQ with fatty acid levels in erythrocyte membranes as biomarkers. PG - 1477-84 LID - 10.1017/S1368980008004503 [doi] AB - OBJECTIVE: To evaluate the validity of the Northern Sweden eighty-four-item FFQ to estimate intake of fatty acids relative to 24 h diet recalls (24-HDR) and fatty acids in erythrocyte membranes. DESIGN: Participants, randomly recruited from the population-based Vasterbotten Intervention Project, answered the eighty-four-item FFQ. During the following year each participant carried out ten 24-HDR. Intake of fatty acids measured by the FFQ was compared with intake by the 24-HDR and fatty acid levels in erythrocytes. SETTING: The county of Vasterbotten in northern Sweden. SUBJECTS: Ninety-six men and ninety-nine women. RESULTS: Spearman correlation coefficients (rs) between intakes of the fatty acids 14 : 0, 15 : 0, 16 : 0, 17 : 0, 18 : 2n-6, 18 : 3n-3, 20 : 5n-3 and 22 : 6n-3 estimated by the FFQ and the 24-HDR were all significant and ranged from 0.29 (22 : 6n-3 in men and women) to 0.60 (16 : 0 in men), whereas significant correlations between FFQ-estimated intake and erythrocyte membrane content were only seen for milk fatty acids 14 : 0, 15 : 0 and 17 : 0 (rs = 0.23-0.34) and fish fatty acids 20 : 5n-3 and 22 : 6n-3 (rs = 0.42-0.51). CONCLUSION: The Northern Sweden eighty-four-item FFQ gives a satisfactory estimate of the intake of fish fatty acids (20 : 5n-3 and 22 : 6n-3) and milk fatty acids (15 : 0 and 17 : 0), whereas its validity for fatty acids 18 : 2n-6 and 18 : 3n-3, derived mainly from vegetable oils, cannot be shown. FAU - Wennberg, Maria AU - Wennberg M AD - Department of Medicine, Skelleftea Hospital, Skelleftea, Sweden. maria.wennberg@envmed.umu.se FAU - Vessby, Bengt AU - Vessby B FAU - Johansson, Ingegerd AU - Johansson I LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Validation Study DEP - 20090115 PL - England TA - Public Health Nutr JT - Public health nutrition JID - 9808463 RN - 0 (Biomarkers) RN - 0 (Fatty Acids) SB - IM MH - Adult MH - Animals MH - Biomarkers/blood MH - Cohort Studies MH - *Diet Surveys MH - Erythrocyte Membrane/*chemistry MH - Fatty Acids/*administration & dosage/analysis MH - Female MH - Humans MH - Male MH - Mental Recall MH - Middle Aged MH - Milk/chemistry MH - Reproducibility of Results MH - Seafood/analysis MH - Statistics, Nonparametric MH - Surveys and Questionnaires/*standards MH - Sweden EDAT- 2009/01/16 09:00 MHDA- 2009/11/10 06:00 CRDT- 2009/01/16 09:00 PHST- 2009/01/16 09:00 [entrez] PHST- 2009/01/16 09:00 [pubmed] PHST- 2009/11/10 06:00 [medline] AID - S1368980008004503 [pii] AID - 10.1017/S1368980008004503 [doi] PST - ppublish SO - Public Health Nutr. 2009 Sep;12(9):1477-84. doi: 10.1017/S1368980008004503. Epub 2009 Jan 15.