PMID- 19149920
OWN - NLM
STAT- MEDLINE
DCOM- 20090324
LR  - 20211203
IS  - 1008-8830 (Print)
IS  - 1008-8830 (Linking)
VI  - 11
IP  - 1
DP  - 2009 Jan
TI  - [Roles of serum and urinary interleukins 13Ralpha2 and other cytokines in 
      pediatric Henoch-Schonlein purpura].
PG  - 37-40
AB  - OBJECTIVE: To study the roles of serum and urinary interleukins (IL)-13Ralpha2, 
      IL-4, IL-6, IL-8 and tumor necrosis factor-alpha(TNF-alpha) in pediatric 
      Henoch-Schonlein purpura (HSP). METHODS: Serum and urinary levels of 
      IL-13Ralpha2, IL-4, IL-6, IL-8 and TNF-alpha were examined using ELISA in 52 
      children with HSP and 45 healthy children. The results were compared between the 
      two groups. RESULTS: Serum levels of IL-13Ralpha2, IL-4, IL-6, IL-8 and TNF-alpha 
      in HSP patients with or without renal lesions were higher than those in the 
      control group (p<0.01 or 0.05). Urinary levels of IL-6 and TNF-alpha in HSP 
      patients without renal lesions were higher than those in the control group 
      (p<0.05). Except for urinary levels of IL-6 and TNF-alpha, urinary IL-13Ralpha2 
      levels in HSP patients with renal lesions (HSPN) were higher than those in the 
      control group (p<0.05). CONCLUSIONS: Cytokines IL-13Ralpha2, IL-4, IL-6, IL-8 and 
      TNF-alpha may play roles in the pathogenesis of pediatric HSP/HSPN.
FAU - Yu, Yan-Hong
AU  - Yu YH
AD  - Department of Pediatrics, Xijing Hospital, Fourth Military Medical University, 
      Xi'an 710032, China.
FAU - Pan, Kai-Li
AU  - Pan KL
FAU - Li, Qi
AU  - Li Q
FAU - Zhang, Bao-Juan
AU  - Zhang BJ
FAU - Huang, Ying
AU  - Huang Y
FAU - Zhang, Jing-Jing
AU  - Zhang JJ
FAU - DU, Li
AU  - DU L
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhongguo Dang Dai Er Ke Za Zhi
JT  - Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
JID - 100909956
RN  - 0 (Cytokines)
RN  - 0 (Interleukin-13 Receptor alpha2 Subunit)
RN  - 0 (Interleukin-6)
RN  - 0 (Tumor Necrosis Factor-alpha)
SB  - IM
MH  - Adolescent
MH  - Child
MH  - Child, Preschool
MH  - Cytokines/*physiology
MH  - Female
MH  - Humans
MH  - IgA Vasculitis/*etiology/immunology
MH  - Interleukin-13 Receptor alpha2 Subunit/blood/*physiology
MH  - Interleukin-6/physiology
MH  - Male
MH  - Tumor Necrosis Factor-alpha/physiology
EDAT- 2009/01/20 09:00
MHDA- 2009/03/25 09:00
CRDT- 2009/01/20 09:00
PHST- 2009/01/20 09:00 [entrez]
PHST- 2009/01/20 09:00 [pubmed]
PHST- 2009/03/25 09:00 [medline]
AID - 1008-8830(2009)01-0037-04 [pii]
PST - ppublish
SO  - Zhongguo Dang Dai Er Ke Za Zhi. 2009 Jan;11(1):37-40.