PMID- 19155097
OWN - NLM
STAT- MEDLINE
DCOM- 20090514
LR  - 20090814
IS  - 1527-3296 (Electronic)
IS  - 0196-6553 (Linking)
VI  - 37
IP  - 3
DP  - 2009 Apr
TI  - Methicillin resistance of airborne coagulase-negative staphylococci in homes of 
      persons having contact with a hospital environment.
PG  - 177-82
LID - 10.1016/j.ajic.2008.09.013 [doi]
AB  - BACKGROUND: The persons having contact with a hospital environment (hospital 
      personnel workers and discharged patients) are highly exposed to colonization 
      with multidrug-resistant bacteria. The aim of this study was to evaluate the 
      airborne Staphylococcus genus features in homes in which inhabitants have had 
      contact with the hospital environment. METHODS: Airborne bacteria were collected 
      using a 6-stage Anderson impactor. The Staphylococcus species composition and 
      resistance to methicillin, and other antimicrobial agents among 3 
      coagulase-negative staphylococci (CNS) species (S cohnii spp cohnii, S 
      epidermidis, S hominis), were determined. Antibiotic resistance of isolates was 
      tested using the agar screen method with methicillin, the polymerase chain 
      reaction technique to detect the mecA gene, and the disk diffusion method. 
      RESULTS: A higher prevalence of methicillin-resistant (MR) strains among the 
      species isolated (40% of S epidermidis, 40% of S hominis, and 60% of S cohnii spp 
      cohnii) was found in homes of persons who had contact with a hospital environment 
      compared with the reference homes (only 12% of S hominis). The mecA gene was 
      revealed in all MR S epidermidis strains and in some MR S hominis (50%) and S 
      cohnii spp cohnii (33%) strains. All isolated MR CNS strains were susceptible to 
      vancomycin, rifampicin, and linezolid. CONCLUSION: High numbers of airborne 
      multidrug-resistant MR CNS in the homes of persons having contact with a hospital 
      environment indicates that such inhabitants pose a risk of intrafamilial 
      spreading of MR strains via air.
FAU - Lis, Danuta O
AU  - Lis DO
AD  - Department of Biohazards, Institute of Occupational Medicine and Environmental 
      Health, Sosnowiec, Poland.
FAU - Pacha, Jerzy Z
AU  - Pacha JZ
FAU - Idzik, Danuta
AU  - Idzik D
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20090119
PL  - United States
TA  - Am J Infect Control
JT  - American journal of infection control
JID - 8004854
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Bacterial Proteins)
RN  - 0 (MecA protein, Staphylococcus epidermidis)
SB  - IM
MH  - *Air Microbiology
MH  - Anti-Bacterial Agents/*pharmacology
MH  - Bacterial Proteins/genetics
MH  - Hospitals
MH  - Humans
MH  - *Methicillin Resistance
MH  - Microbial Sensitivity Tests
MH  - Residence Characteristics
MH  - Staphylococcus/*drug effects/*isolation & purification
EDAT- 2009/01/22 09:00
MHDA- 2009/05/15 09:00
CRDT- 2009/01/22 09:00
PHST- 2008/06/12 00:00 [received]
PHST- 2008/09/12 00:00 [revised]
PHST- 2008/09/12 00:00 [accepted]
PHST- 2009/01/22 09:00 [entrez]
PHST- 2009/01/22 09:00 [pubmed]
PHST- 2009/05/15 09:00 [medline]
AID - S0196-6553(08)00785-2 [pii]
AID - 10.1016/j.ajic.2008.09.013 [doi]
PST - ppublish
SO  - Am J Infect Control. 2009 Apr;37(3):177-82. doi: 10.1016/j.ajic.2008.09.013. Epub 
      2009 Jan 19.