PMID- 19155683 OWN - NLM STAT- MEDLINE DCOM- 20090424 LR - 20190816 IS - 1124-9390 (Print) IS - 1124-9390 (Linking) VI - 16 IP - 4 DP - 2008 Dec TI - [Tuberculosis-associated immune reconstitution inflammatory syndrome]. PG - 193-9 AB - The prognosis of HIV-infected patients has dramatically improved since the advent of HAART. The immune recovery associated with HAART may result in immuno-pathological reactions and clinical deterioration when HAART is initiated in patients with tuberculosis (TB). This phenomenon is defined as immune reconstitution inflammatory syndrome (IRIS). In this review, we summarise the epidemiology, clinical presentations and management of TB-associated IRIS. FAU - Leone, S AU - Leone S AD - U.O.C. Malattie Infettive, AORN San Giuseppe Moscati, Avellino, Italy. FAU - Nicastri, E AU - Nicastri E FAU - Giglio, S AU - Giglio S FAU - Corpolongo, A AU - Corpolongo A FAU - Narciso, P AU - Narciso P FAU - Acone, N AU - Acone N LA - ita PT - English Abstract PT - Journal Article PT - Review TT - Sindrome infiammatoria da immunoricostituzione associata alla tubercolosi. PL - Italy TA - Infez Med JT - Le infezioni in medicina JID - 9613961 RN - 0 (Antitubercular Agents) RN - 0 (Glucocorticoids) SB - IM MH - AIDS-Related Opportunistic Infections/diagnosis/drug therapy/epidemiology/*immunology MH - Antiretroviral Therapy, Highly Active/*adverse effects MH - Antitubercular Agents/therapeutic use MH - Drug Therapy, Combination MH - Evidence-Based Medicine MH - Glucocorticoids/therapeutic use MH - Humans MH - Immune Reconstitution Inflammatory Syndrome/chemically induced/diagnosis/*etiology/immunology/microbiology MH - Incidence MH - Prevalence MH - Risk Factors MH - Rome/epidemiology MH - Treatment Outcome MH - Tuberculosis, Pulmonary/diagnosis/drug therapy/epidemiology/*immunology RF - 48 EDAT- 2009/01/22 09:00 MHDA- 2009/04/25 09:00 CRDT- 2009/01/22 09:00 PHST- 2009/01/22 09:00 [entrez] PHST- 2009/01/22 09:00 [pubmed] PHST- 2009/04/25 09:00 [medline] PST - ppublish SO - Infez Med. 2008 Dec;16(4):193-9.