PMID- 19157098
OWN - NLM
STAT- MEDLINE
DCOM- 20090528
LR  - 20221207
IS  - 1009-3591 (Print)
IS  - 1009-3591 (Linking)
VI  - 14
IP  - 10
DP  - 2008 Oct
TI  - [Selective serotonin reuptake inhibitor is more likely to induce sexual 
      dysfunction than mirtazapine in treating depression].
PG  - 896-9
AB  - OBJECTIVE: To compare the incidences of sexual dysfunction induced by mirtazapine 
      and SSRI in the treatment of patients with depression. METHODS: Using key-word 
      retrieval from the compact disks of the Chinese biological medicine (CBM) data 
      base, we analyzed the rates of sexual dysfunction from the published clinical 
      control trials on depression treated with mirtazapine and SSRI by applying the 
      fixed effects model (FEM) of evidence-based medicine (EBM). RESULTS: Among 1108 
      cases in 14 studies, there were 5 cases of mirtazapine-induced and 106 cases of 
      SSRI-induced sexual dysfunction, accounting for 0.90% and 19.2% respectively, OR 
      = 0.07 (95% CI: 0.04-0.14), Z = 8.03, P < 0.01. CONCLUSION: SSRI is far more 
      likely to induce sexual dysfunction than mirtazapine in the treatment of 
      depression.
FAU - Chen, Zheng-xin
AU  - Chen ZX
AD  - Department of Psychiatry, Zhejiang Province Mental Health Center, Tongde Hospital 
      of Zhejiang Province, Hangzhou, Zhejiang 310012, China.
FAU - Wang, He-qiu
AU  - Wang HQ
FAU - Jin, Wei-dong
AU  - Jin WD
LA  - chi
PT  - Journal Article
PT  - Meta-Analysis
PL  - China
TA  - Zhonghua Nan Ke Xue
JT  - Zhonghua nan ke xue = National journal of andrology
JID - 101093592
RN  - 0 (Antidepressive Agents, Tricyclic)
RN  - 0 (Serotonin Uptake Inhibitors)
RN  - 250PJI13LM (Mianserin)
RN  - A051Q2099Q (Mirtazapine)
SB  - IM
MH  - Antidepressive Agents, Tricyclic/*adverse effects
MH  - Depressive Disorder/drug therapy
MH  - Erectile Dysfunction/*chemically induced
MH  - Humans
MH  - Male
MH  - Mianserin/adverse effects/*analogs & derivatives
MH  - Mirtazapine
MH  - Selective Serotonin Reuptake Inhibitors/*adverse effects
EDAT- 2009/01/23 09:00
MHDA- 2009/05/29 09:00
CRDT- 2009/01/23 09:00
PHST- 2009/01/23 09:00 [entrez]
PHST- 2009/01/23 09:00 [pubmed]
PHST- 2009/05/29 09:00 [medline]
PST - ppublish
SO  - Zhonghua Nan Ke Xue. 2008 Oct;14(10):896-9.