PMID- 19165622
OWN - NLM
STAT- MEDLINE
DCOM- 20090709
LR  - 20211020
IS  - 1875-8312 (Electronic)
IS  - 1569-5794 (Linking)
VI  - 25 Suppl 1
DP  - 2009 Apr
TI  - Frequency and distribution of late gadolinium enhancement in magnetic resonance 
      imaging of patients with apical hypertrophic cardiomyopathy and patients with 
      asymmetrical hypertrophic cardiomyopathy: a comparative study.
PG  - 131-8
LID - 10.1007/s10554-008-9406-1 [doi]
AB  - Our aim was to compare the frequency and distribution of late gadolinium 
      enhancement (LGE) on contrast MRI between hypertrophic cardiomyopathy (HCM) 
      patients with apical hypertrophic cardiomyopathy (APH) and those with 
      asymmetrical septal hypertrophy (ASH). We studied 66 patients with HCM (50 men 
      and 16 women; average age: 58.8 +/- 29.8 years) who had undergone MRI. All the 
      MRI examinations were performed using a 1.5 T system. LGE images were acquired 
      using the inversion recovery segmented spoiled-gradient echo and phase-sensitive 
      inversion recovery methods. We evaluated 17 segments of the left ventricle as 
      defined by the American Heart Association criteria for LGE determination. LGE was 
      detected at the junction of the right ventricle and the interventricular septum 
      in 25 (73.5%) of the 34 HCM patients with ASH and in the apex of the heart in 13 
      (40.6%) of the 32 patients with APH. LGE-positive areas were more widely 
      distributed in the case of the ASH group than in the case of the APH group. The 
      distribution of LGE was clearly different between the two groups (Fisher's exact 
      probability test, P = 0.0068). The number of LGE-positive cases and LGE-positive 
      segments were significantly higher in the ASH group than in the APH group and 
      there was a significant difference in the distribution of the LGE-positive areas 
      between the two groups. LGE was mainly detected in the hypertrophied areas of the 
      myocardium.
FAU - Yamada, Masao
AU  - Yamada M
AD  - Department of Cardiology, Tokyo Medical University, Tokyo, Japan.
FAU - Teraoka, Kunihiko
AU  - Teraoka K
FAU - Kawade, Masafumi
AU  - Kawade M
FAU - Hirano, Masaharu
AU  - Hirano M
FAU - Yamashina, Akira
AU  - Yamashina A
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20090123
PL  - United States
TA  - Int J Cardiovasc Imaging
JT  - The international journal of cardiovascular imaging
JID - 100969716
RN  - 0 (Contrast Media)
RN  - K2I13DR72L (Gadolinium DTPA)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cardiomyopathy, Hypertrophic/*pathology
MH  - *Contrast Media
MH  - Disease Progression
MH  - Electrocardiography
MH  - Female
MH  - *Gadolinium DTPA
MH  - Humans
MH  - Image Interpretation, Computer-Assisted
MH  - *Magnetic Resonance Imaging, Cine
MH  - Male
MH  - Middle Aged
MH  - Myocardium/*pathology
MH  - Predictive Value of Tests
MH  - Retrospective Studies
EDAT- 2009/01/24 09:00
MHDA- 2009/07/10 09:00
CRDT- 2009/01/24 09:00
PHST- 2008/12/12 00:00 [received]
PHST- 2008/12/15 00:00 [accepted]
PHST- 2009/01/24 09:00 [entrez]
PHST- 2009/01/24 09:00 [pubmed]
PHST- 2009/07/10 09:00 [medline]
AID - 10.1007/s10554-008-9406-1 [doi]
PST - ppublish
SO  - Int J Cardiovasc Imaging. 2009 Apr;25 Suppl 1:131-8. doi: 
      10.1007/s10554-008-9406-1. Epub 2009 Jan 23.