PMID- 19168220
OWN - NLM
STAT- MEDLINE
DCOM- 20090320
LR  - 20151119
IS  - 1549-4713 (Electronic)
IS  - 0161-6420 (Linking)
VI  - 116
IP  - 3
DP  - 2009 Mar
TI  - Responsiveness and clinically important differences for the VF-14 index, SF-36, 
      and visual acuity in patients undergoing cataract surgery.
PG  - 418-424.e1
LID - 10.1016/j.ophtha.2008.11.020 [doi]
AB  - OBJECTIVE: To assess visual acuity (VA) and 2 questionnaires of health-related 
      quality of life--the Visual Function 14 (VF-14) index and the Medical Outcomes 
      Study Short Form 36 Health Survey (SF-36)--as instruments for capturing 
      clinically important changes after cataract surgery. DESIGN: Prospective, 
      observational study. PARTICIPANTS: Four thousand three hundred fifty-six 
      consecutive patients attending ophthalmologic clinics in 17 hospitals in 
      preparation for cataract surgery were recruited. METHODS: Clinical data were 
      collected in the visit before the intervention and 6 weeks after surgery by 
      ophthalmologists. Patients completed the questionnaires before surgery and 3 
      months after surgery. MAIN OUTCOME MEASURES: The VF-14 and SF-36 questionnaire 
      results obtained before surgery and 3 months after the procedure and VA before 
      the procedure and 6 weeks afterward. RESULTS: Positive mean changes in VA (+0.47) 
      and VF-14 results (+24.03) indicated significant improvements after cataract 
      surgery that were not reflected in changes in SF-36 domains (from 1.86 to 5.62). 
      Responsiveness parameters demonstrated large changes in VA and VF-14 scores but 
      not in SF-36 domains. The minimal clinically important differences (MCID) after 
      surgery were 0.41 for VA and 15.57 for VF-14 results; the minimal detectable 
      change (MDC) for VF-14 was 10.81. CONCLUSIONS: Visual acuity and VF-14 scores, 
      but not SF-36 scores, are appropriate instruments for capturing clinically 
      important changes after cataract surgery. The MCID and MDC values obtained 
      herein, although not absolute thresholds, may aid in the interpretation of 
      changes in VA and VF-14 scores.
FAU - Bilbao, Amaia
AU  - Bilbao A
AD  - Fundacion Vasca de Innovacion e Investigacion Sanitarias (BIOEF)-CIBER 
      Epidemiologia y Salud Publica, Sondika, Bizkaia, Spain. abilbao@bioef.org
FAU - Quintana, Jose M
AU  - Quintana JM
FAU - Escobar, Antonio
AU  - Escobar A
FAU - Garcia, Susana
AU  - Garcia S
FAU - Andradas, Elena
AU  - Andradas E
FAU - Bare, Marisa
AU  - Bare M
FAU - Elizalde, Belen
AU  - Elizalde B
CN  - IRYSS-Cataract Group
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20090124
PL  - United States
TA  - Ophthalmology
JT  - Ophthalmology
JID - 7802443
SB  - IM
MH  - Aged
MH  - *Cataract Extraction
MH  - Female
MH  - Health Status
MH  - Humans
MH  - Lens Implantation, Intraocular
MH  - Male
MH  - Prospective Studies
MH  - *Quality of Life
MH  - *Sickness Impact Profile
MH  - Surveys and Questionnaires
MH  - Visual Acuity/*physiology
FIR - Martinez-Tapias, Jesus
IR  - Martinez-Tapias J
FIR - Aguayo, Eduardo
IR  - Aguayo E
FIR - Perea-Milla, Emilio
IR  - Perea-Milla E
FIR - Lacalle, Juan Ramon
IR  - Lacalle JR
FIR - Navarro, Gemma
IR  - Navarro G
FIR - Blasco, Juan Antonio
IR  - Blasco JA
FIR - de Larrea, Nerea Fernandez
IR  - de Larrea NF
FIR - Arostegui, Inmaculada
IR  - Arostegui I
FIR - Alberdi, Txomin
IR  - Alberdi T
FIR - Begiristain, Jose M
IR  - Begiristain JM
FIR - Garai, Idoia
IR  - Garai I
FIR - Aizpuru, Felipe
IR  - Aizpuru F
FIR - Gonzalez, Nerea
IR  - Gonzalez N
FIR - Lafuente, Iratxe
IR  - Lafuente I
FIR - Aguirre, Urko
IR  - Aguirre U
EDAT- 2009/01/27 09:00
MHDA- 2009/03/21 09:00
CRDT- 2009/01/27 09:00
PHST- 2008/07/22 00:00 [received]
PHST- 2008/10/22 00:00 [revised]
PHST- 2008/11/24 00:00 [accepted]
PHST- 2009/01/27 09:00 [entrez]
PHST- 2009/01/27 09:00 [pubmed]
PHST- 2009/03/21 09:00 [medline]
AID - S0161-6420(08)01244-X [pii]
AID - 10.1016/j.ophtha.2008.11.020 [doi]
PST - ppublish
SO  - Ophthalmology. 2009 Mar;116(3):418-424.e1. doi: 10.1016/j.ophtha.2008.11.020. 
      Epub 2009 Jan 24.