PMID- 1917743
OWN - NLM
STAT- MEDLINE
DCOM- 19911113
LR  - 20171213
IS  - 8750-7587 (Print)
IS  - 0161-7567 (Linking)
VI  - 71
IP  - 1
DP  - 1991 Jul
TI  - Additive effects of training and high-fat diet on energy metabolism during 
      exercise.
PG  - 197-203
AB  - This study was conducted to obtain additional information about the adaptations 
      after 12 wk of high-fat diet (HFD) per se or HFD combined with endurance training 
      in the rat using a two [diet: carbohydrate (CHO) or HFD] by two (training: 
      sedentary or trained) by two (condition at death: rested or exercised) factorial 
      design. Adaptation to prolonged HFD increases maximal O2 uptake (VO2max; 13%, P 
      less than 0.05) and submaximal running endurance (+64%, P less than 0.05). This 
      enhancement in exercise capacity could be attributed to 1) an increase in 
      skeletal muscle aerobic enzyme activities (3-hydroxyacyl-CoA dehydrogenase and 
      citrate synthase in soleus and red quadriceps) or 2) a decrease in liver glycogen 
      breakdown in response to 1 h exercise at 80% VO2max. When training is 
      superimposed to HFD, the most prominent finding provided by this study is that 
      the diet-induced effects are cumulative with the well-known training effect on 
      VO2max, exercise endurance, oxidative capacity of red muscle, and metabolic 
      responses to exercise, with a further reduction in liver glycogen breakdown.
FAU - Simi, B
AU  - Simi B
AD  - Laboratoire de Physiologie, Faculte de Medecine, Unite de Recherche Associee 1341 
      Centre National de la Recherche Scientifique, Lyon, France.
FAU - Sempore, B
AU  - Sempore B
FAU - Mayet, M H
AU  - Mayet MH
FAU - Favier, R J
AU  - Favier RJ
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Appl Physiol (1985)
JT  - Journal of applied physiology (Bethesda, Md. : 1985)
JID - 8502536
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats)
RN  - 0 (Liver Glycogen)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Animals
MH  - Body Weight
MH  - Diet
MH  - Dietary Carbohydrates/pharmacology
MH  - Dietary Fats/*pharmacology
MH  - Energy Metabolism/*drug effects
MH  - Glucose/metabolism
MH  - Glycolysis/drug effects
MH  - Liver/drug effects/metabolism
MH  - Liver Glycogen/metabolism
MH  - Male
MH  - Muscles/enzymology/physiology
MH  - Oxygen Consumption/drug effects
MH  - *Physical Conditioning, Animal
MH  - Rats
MH  - Rats, Inbred Strains
OID - NASA: 92011215
EDAT- 1991/07/01 00:00
MHDA- 1991/07/01 00:01
CRDT- 1991/07/01 00:00
PHST- 1991/07/01 00:00 [pubmed]
PHST- 1991/07/01 00:01 [medline]
PHST- 1991/07/01 00:00 [entrez]
AID - 10.1152/jappl.1991.71.1.197 [doi]
PST - ppublish
SO  - J Appl Physiol (1985). 1991 Jul;71(1):197-203. doi: 10.1152/jappl.1991.71.1.197.