PMID- 19182443
OWN - NLM
STAT- MEDLINE
DCOM- 20090511
LR  - 20190911
IS  - 1880-3989 (Electronic)
IS  - 0388-1350 (Linking)
VI  - 34
IP  - 1
DP  - 2009 Feb
TI  - Effects of restricted feeding on blood parameters in pregnant rabbits.
PG  - 129-37
AB  - The effects of restricted feeding (20 g/day from gestational day (GD) 6 to 28) on 
      pregnancy outcome and blood parameters were examined in pregnant rabbits. As 
      compared with the group which was allowed free access to diet throughout the 
      gestational period (NT group), the group subjected to restricted feeding (R 
      group) showed significantly lower values in many parameters such as total 
      protein, albumin and triglyceride on GDs 22 and 28, reflecting low nutritive 
      conditions. In addition, there were significant changes in blood 
      coagulation-related parameters, suggesting an imbalance between coagulation and 
      anti-coagulation factors. Moreover, abortions occurred in about half of the 
      animals of the R group between GDs 23 and 27. When aborted rabbits were compared 
      with those which could maintain pregnancy under restricted feeding, total 
      protein, albumin, platelets and antithrombin III values and especially blood 
      progesterone concentration were significantly lower in aborted rabbits on GD 22, 
      prior to occurrence of abortion. These results suggested that abortions due to 
      restricted feeding might be brought about by lower nutritive conditions, an 
      imbalance of blood coagulation-related factors and lower blood progesterone 
      concentrations.
FAU - Matsuoka, Tetsuya
AU  - Matsuoka T
AD  - Kannami Laboratory, Bozo Research Center Inc., Japan.
FAU - Mizuguchi, Hiroyasu
AU  - Mizuguchi H
FAU - Mizoguchi, Yasumoto
AU  - Mizoguchi Y
FAU - Endho, Takako
AU  - Endho T
FAU - Kamata, Ryo
AU  - Kamata R
FAU - Fukuda, Kazuya
AU  - Fukuda K
FAU - Ishikawa, Tsutomu
AU  - Ishikawa T
FAU - Asano, Yuzo
AU  - Asano Y
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Japan
TA  - J Toxicol Sci
JT  - The Journal of toxicological sciences
JID - 7805798
RN  - 0 (Blood Coagulation Factors)
RN  - 4G7DS2Q64Y (Progesterone)
SB  - IM
MH  - Abortion, Veterinary/blood
MH  - Animals
MH  - Blood Chemical Analysis/*methods/statistics & numerical data
MH  - Blood Coagulation/physiology
MH  - Blood Coagulation Factors/analysis
MH  - Blood Coagulation Tests/methods/statistics & numerical data
MH  - Cesarean Section/veterinary
MH  - Female
MH  - *Food Deprivation
MH  - Gestational Age
MH  - Pregnancy
MH  - Pregnancy Outcome
MH  - Pregnancy, Animal/*blood
MH  - Progesterone/blood
MH  - Rabbits
MH  - Time Factors
MH  - Weight Gain
MH  - Weight Loss
EDAT- 2009/02/03 09:00
MHDA- 2009/05/12 09:00
CRDT- 2009/02/03 09:00
PHST- 2009/02/03 09:00 [entrez]
PHST- 2009/02/03 09:00 [pubmed]
PHST- 2009/05/12 09:00 [medline]
AID - JST.JSTAGE/jts/34.129 [pii]
AID - 10.2131/jts.34.129 [doi]
PST - ppublish
SO  - J Toxicol Sci. 2009 Feb;34(1):129-37. doi: 10.2131/jts.34.129.