PMID- 19184198
OWN - NLM
STAT- MEDLINE
DCOM- 20091224
LR  - 20090706
IS  - 1432-086X (Electronic)
IS  - 0174-1551 (Linking)
VI  - 32
IP  - 4
DP  - 2009 Jul
TI  - Embolization as an alternative treatment of insulinoma in a patient with multiple 
      endocrine neoplasia type 1 syndrome.
PG  - 807-11
LID - 10.1007/s00270-008-9499-x [doi]
AB  - Insulinoma is a rare neuroendocrine tumor, most commonly originating from the 
      pancreas, which is either sporadic or familial as a component of multiple 
      endocrine neoplasia type 1 syndrome (MEN1). It is characterized by increased 
      insulin secretion leading to hypoglycemia. Surgical removal is considered the 
      treatment of choice, with limited side effects and relatively low morbidity and 
      mortality, both being improved by the laparoscopic procedure. We present the case 
      of a 30-year-old patient with MEN1 and recurrent insulinoma with severe 
      hypoglycemic episodes who could not be surgically treated due to the adherence of 
      the tumor to large blood vessels and to prior multiple surgical operations. He 
      was treated by repeated embolization using spherical polyvinyl alcohol particles, 
      resulting in shrinkage of the tumor, improvement of the frequency and severity of 
      the hypoglycemic episodes, and better quality of life.
FAU - Peppa, Melpomeni
AU  - Peppa M
AD  - Endocrine Unit, Second Department of Internal Medicine-Propaedeutic, Research 
      Institute and Diabetes Center, Athens University Medical School, Attikon 
      University Hospital, Athens, Greece. molypepa@otenet.gr
FAU - Brountzos, Epsilonlias
AU  - Brountzos E
FAU - Economopoulos, Nicolaos
AU  - Economopoulos N
FAU - Boutati, Eleni
AU  - Boutati E
FAU - Pikounis, Vasilios
AU  - Pikounis V
FAU - Patapis, Paul
AU  - Patapis P
FAU - Economopoulos, Theofanis
AU  - Economopoulos T
FAU - Raptis, Sotirios A
AU  - Raptis SA
FAU - Hadjidakis, Dimitrios
AU  - Hadjidakis D
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20090130
PL  - United States
TA  - Cardiovasc Intervent Radiol
JT  - Cardiovascular and interventional radiology
JID - 8003538
SB  - IM
MH  - Adult
MH  - Angiography, Digital Subtraction
MH  - Embolization, Therapeutic/*methods
MH  - Humans
MH  - Imaging, Three-Dimensional
MH  - Insulinoma/diagnosis/*therapy
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Multiple Endocrine Neoplasia Type 1/*pathology
MH  - Pancreatic Neoplasms/diagnosis/*therapy
MH  - Quality of Life
EDAT- 2009/02/03 09:00
MHDA- 2009/12/25 06:00
CRDT- 2009/02/03 09:00
PHST- 2008/09/24 00:00 [received]
PHST- 2008/12/08 00:00 [accepted]
PHST- 2008/12/04 00:00 [revised]
PHST- 2009/02/03 09:00 [entrez]
PHST- 2009/02/03 09:00 [pubmed]
PHST- 2009/12/25 06:00 [medline]
AID - 10.1007/s00270-008-9499-x [doi]
PST - ppublish
SO  - Cardiovasc Intervent Radiol. 2009 Jul;32(4):807-11. doi: 
      10.1007/s00270-008-9499-x. Epub 2009 Jan 30.