PMID- 19187516 OWN - NLM STAT- MEDLINE DCOM- 20090406 LR - 20181201 IS - 1365-3156 (Electronic) IS - 1360-2276 (Linking) VI - 14 IP - 3 DP - 2009 Mar TI - Cluster-sample surveys and lot quality assurance sampling to evaluate yellow fever immunisation coverage following a national campaign, Bolivia, 2007. PG - 355-61 LID - 10.1111/j.1365-3156.2009.02231.x [doi] AB - OBJECTIVE: To estimate the yellow fever (YF) vaccine coverage for the endemic and non-endemic areas of Bolivia and to determine whether selected districts had acceptable levels of coverage (>70%). METHODS: We conducted two surveys of 600 individuals (25 x 12 clusters) to estimate coverage in the endemic and non-endemic areas. We assessed 11 districts using lot quality assurance sampling (LQAS). The lot (district) sample was 35 individuals with six as decision value (alpha error 6% if true coverage 70%; beta error 6% if true coverage 90%). To increase feasibility, we divided the lots into five clusters of seven individuals; to investigate the effect of clustering, we calculated alpha and beta by conducting simulations where each cluster's true coverage was sampled from a normal distribution with a mean of 70% or 90% and standard deviations of 5% or 10%. RESULTS: Estimated coverage was 84.3% (95% CI: 78.9-89.7) in endemic areas, 86.8% (82.5-91.0) in non-endemic and 86.0% (82.8-89.1) nationally. LQAS showed that four lots had unacceptable coverage levels. In six lots, results were inconsistent with the estimated administrative coverage. The simulations suggested that the effect of clustering the lots is unlikely to have significantly increased the risk of making incorrect accept/reject decisions. CONCLUSIONS: Estimated YF coverage was high. Discrepancies between administrative coverage and LQAS results may be due to incorrect population data. Even allowing for clustering in LQAS, the statistical errors would remain low. Catch-up campaigns are recommended in districts with unacceptable coverage. FAU - Pezzoli, Lorenzo AU - Pezzoli L AD - European Programme for Intervention Epidemiology Training, European Centre for Disease Control, Stockholm, Sweden. lorenzo.pezzoli@hpa.org.uk FAU - Pineda, Silvia AU - Pineda S FAU - Halkyer, Percy AU - Halkyer P FAU - Crespo, Gladys AU - Crespo G FAU - Andrews, Nick AU - Andrews N FAU - Ronveaux, Olivier AU - Ronveaux O LA - eng PT - Journal Article DEP - 20090128 PL - England TA - Trop Med Int Health JT - Tropical medicine & international health : TM & IH JID - 9610576 RN - 0 (Yellow Fever Vaccine) SB - IM MH - Adolescent MH - Adult MH - Bolivia/epidemiology MH - Child MH - Child, Preschool MH - Endemic Diseases MH - Epidemiologic Methods MH - Female MH - Humans MH - Immunization Programs/*standards MH - Lot Quality Assurance Sampling MH - Male MH - Program Evaluation MH - Vaccination/statistics & numerical data MH - Yellow Fever/epidemiology/prevention & control MH - Yellow Fever Vaccine/*administration & dosage EDAT- 2009/02/04 09:00 MHDA- 2009/04/07 09:00 CRDT- 2009/02/04 09:00 PHST- 2009/02/04 09:00 [entrez] PHST- 2009/02/04 09:00 [pubmed] PHST- 2009/04/07 09:00 [medline] AID - TMI2231 [pii] AID - 10.1111/j.1365-3156.2009.02231.x [doi] PST - ppublish SO - Trop Med Int Health. 2009 Mar;14(3):355-61. doi: 10.1111/j.1365-3156.2009.02231.x. Epub 2009 Jan 28.