PMID- 19187651
OWN - NLM
STAT- MEDLINE
DCOM- 20090522
LR  - 20181201
IS  - 2542-5641 (Electronic)
IS  - 0366-6999 (Linking)
VI  - 122
IP  - 2
DP  - 2009 Jan 20
TI  - Human umbilical cord mesenchymal stem cells and the treatment of spinal cord 
      injury.
PG  - 225-31
AB  - OBJECTIVE: To review the recent studies about human umbilical cord mesenchymal 
      stem cells (hUCMSCs) and advances in the treatment of spinal cord injury. Data 
      sources Published articles (1983 - 2007) about hUCMSCs and spinal cord injury 
      were selected using Medline. Study selection Articles selected were relevant to 
      development of mesenchymal stem cells (MSCs) for transplantation in spinal cord 
      injury therapy. Of 258 originally identified articles 51 were selected that 
      specifically addressed the stated purpose. RESULTS: Recent work has revealed that 
      hUCMSCs share most of the characteristics with MSCs derived from bone marrow and 
      are more appropriate to transplantation for cell based therapies. CONCLUSIONS: 
      Human umbilical cord could be regarded as a source of MSCs for experimental and 
      clinical needs. In addition, as a peculiar source of stem cells, hUCMSCs may play 
      an important role in the treatment of spinal cord injury.
FAU - Cao, Fu-jiang
AU  - Cao FJ
AD  - Department of Orthopaedics, General Hospital of Tianjin Medical University, 
      Tianjin 300052, China.
FAU - Feng, Shi-qing
AU  - Feng SQ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - China
TA  - Chin Med J (Engl)
JT  - Chinese medical journal
JID - 7513795
SB  - IM
MH  - Humans
MH  - Mesenchymal Stem Cells/*cytology/physiology
MH  - Models, Biological
MH  - Spinal Cord Injuries/pathology/*therapy
MH  - Stem Cell Transplantation
MH  - Umbilical Cord/*cytology
RF  - 51
EDAT- 2009/02/04 09:00
MHDA- 2009/05/23 09:00
CRDT- 2009/02/04 09:00
PHST- 2009/02/04 09:00 [entrez]
PHST- 2009/02/04 09:00 [pubmed]
PHST- 2009/05/23 09:00 [medline]
PST - ppublish
SO  - Chin Med J (Engl). 2009 Jan 20;122(2):225-31.