PMID- 19187896
OWN - NLM
STAT- MEDLINE
DCOM- 20090519
LR  - 20090203
IS  - 1558-1527 (Electronic)
IS  - 1558-1527 (Linking)
VI  - 80
IP  - 2
DP  - 2009 Feb
TI  - Advanced visual field loss secondary to optic nerve head drusen: case report and 
      literature review.
PG  - 83-100
LID - 10.1016/j.optm.2008.11.004 [doi]
AB  - BACKGROUND: Optic nerve head drusen (ONHD) is a relatively uncommon condition 
      that results from calcific degeneration of axons within the optic nerve. The 
      abnormal drusen bodies can enlarge, compressing normal nerve structures, and 
      ultimately may result in vision loss. Drusen often are discovered through 
      clinical evaluation with a dilated funduscopic examination. Ancillary testing, 
      including computed tomographic (CT) imaging, B-scan ultrasonography, 
      autofluorescence imaging, nerve fiber layer imaging, and threshold visual field 
      evaluation are helpful to confirm the existence of ONHD and to evaluate for 
      progression of this condition. CASE REPORT: This case report discusses the 
      clinical presentation of a patient with advanced visual field loss from ONHD and 
      the ancillary testing used to confirm the diagnosis. A complete review of 
      literature on ONHD is discussed. CONCLUSIONS: Currently, there is no cure or 
      direct treatment for progressive vision loss or complications that may develop 
      from ONHD. Useful diagnostic tools include serial automated threshold visual 
      fields, nerve fiber layer analysis, and fundus photography. It is suggested that 
      ocular hypotensive agents be used to lower intraocular pressure prophylactically 
      to prevent further nerve fiber layer and optic nerve damage.
FAU - Morris, Robert W
AU  - Morris RW
AD  - W.G. Hefner VA Medical Center, Salisbury, North Carolina, USA. 
      robert.morris2@va.gov
FAU - Ellerbrock, Joy M
AU  - Ellerbrock JM
FAU - Hamp, Ania M
AU  - Hamp AM
FAU - Joy, Jeffrey T
AU  - Joy JT
FAU - Roels, Philip
AU  - Roels P
FAU - Davis, Charles N Jr
AU  - Davis CN Jr
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Optometry
JT  - Optometry (St. Louis, Mo.)
JID - 100912421
SB  - IM
MH  - Fundus Oculi
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Optic Disk Drusen/*complications/diagnosis
MH  - Scotoma/*complications/diagnosis/physiopathology
MH  - Tomography, Optical Coherence
MH  - Visual Fields
RF  - 148
EDAT- 2009/02/04 09:00
MHDA- 2009/05/20 09:00
CRDT- 2009/02/04 09:00
PHST- 2008/11/20 00:00 [accepted]
PHST- 2009/02/04 09:00 [entrez]
PHST- 2009/02/04 09:00 [pubmed]
PHST- 2009/05/20 09:00 [medline]
AID - S1529-1839(08)00661-1 [pii]
AID - 10.1016/j.optm.2008.11.004 [doi]
PST - ppublish
SO  - Optometry. 2009 Feb;80(2):83-100. doi: 10.1016/j.optm.2008.11.004.