PMID- 19192228
OWN - NLM
STAT- MEDLINE
DCOM- 20091201
LR  - 20211020
IS  - 1440-1843 (Electronic)
IS  - 1323-7799 (Linking)
VI  - 14
IP  - 4
DP  - 2009 May
TI  - Pulmonary complications of immune reconstitution inflammatory syndromes in 
      HIV-infected patients.
PG  - 486-94
LID - 10.1111/j.1440-1843.2008.01468.x [doi]
AB  - Immune reconstitution inflammatory syndrome (IRIS) describes a paradoxical 
      worsening of clinical status related to recovery of the immune system, as can 
      occur after the initiation of highly active antiretroviral therapy (HAART) in 
      HIV-infected patients. Most commonly, IRIS results from opportunistic infections 
      that can unmask or develop paradoxical worsening following HAART. Cancers, 
      autoimmune conditions and sarcoidosis have also been associated with IRIS. 
      Pulmonary complications may be frequently encountered. This article reviews the 
      types and clinical presentation of IRIS, with a focus on the pulmonary 
      manifestations. Management and outcome of IRIS are considered.
FAU - Crothers, Kristina
AU  - Crothers K
AD  - Section of Pulmonary and Critical Care Medicine, Department of Internal Medicine, 
      Yale University School of Medicine, New Haven, Connecticut, USA. 
      kristina.crothers@yale.edu
FAU - Huang, Laurence
AU  - Huang L
LA  - eng
GR  - R01 HL090335-02/HL/NHLBI NIH HHS/United States
GR  - R01 HL090342/HL/NHLBI NIH HHS/United States
GR  - K24 HL087713/HL/NHLBI NIH HHS/United States
GR  - R01 HL090335/HL/NHLBI NIH HHS/United States
GR  - K24 HL087713-03/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Review
PL  - Australia
TA  - Respirology
JT  - Respirology (Carlton, Vic.)
JID - 9616368
SB  - IM
MH  - AIDS-Related Opportunistic Infections/*diagnosis/etiology/*therapy
MH  - Antiretroviral Therapy, Highly Active
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*diagnosis/etiology/*therapy
MH  - Lung Diseases, Fungal/diagnosis/*etiology/therapy
MH  - Tuberculosis, Pulmonary/diagnosis/*etiology/therapy
RF  - 64
EDAT- 2009/02/05 09:00
MHDA- 2009/12/16 06:00
CRDT- 2009/02/05 09:00
PHST- 2009/02/05 09:00 [entrez]
PHST- 2009/02/05 09:00 [pubmed]
PHST- 2009/12/16 06:00 [medline]
AID - RES1468 [pii]
AID - 10.1111/j.1440-1843.2008.01468.x [doi]
PST - ppublish
SO  - Respirology. 2009 May;14(4):486-94. doi: 10.1111/j.1440-1843.2008.01468.x.