PMID- 19214158
OWN - NLM
STAT- MEDLINE
DCOM- 20090219
LR  - 20220330
IS  - 1545-861X (Electronic)
IS  - 0149-2195 (Linking)
VI  - 58
IP  - 5
DP  - 2009 Feb 13
TI  - Increase in Coccidioidomycosis - California, 2000-2007.
PG  - 105-9
AB  - Coccidioidomycosis is an infection resulting from inhalation of airborne spores 
      of Coccidioides immitis or Coccidioides posadasii, soil-dwelling fungi endemic to 
      California's San Joaquin Valley; southern regions of Arizona, Utah, Nevada, and 
      New Mexico; western Texas; and regions of Mexico and Central and South America. 
      Of an estimated 150,000 new infections annually in the United States, 
      approximately 60% are asymptomatic. Patients with symptoms usually experience a 
      self-limited influenza-like illness (ILI), although some develop severe 
      pneumonia. Fewer than 1% of patients develop disseminated disease. Infection 
      usually produces immunity to reinfection. During 1995--2000, the number of 
      reported coccidioidomycosis cases in California averaged 2.5 per 100,000 
      population annually. However, from 2000 to 2006, the incidence rate more than 
      tripled, increasing from 2.4 to 8.0 per 100,000 population. To characterize this 
      increase, the California Department of Public Health (CDPH) analyzed case and 
      hospitalization data for the period 2000--2007 and preliminary case report data 
      for 2008. The results indicated that, during 2000--2006, the number of reported 
      cases and hospitalizations for coccidioidomycosis in California increased each 
      year, before decreasing in 2007. Annual incidence during 2000--2007 was highest 
      in Kern County (150.0 cases per 100,000 population), and the hospitalization rate 
      was highest among non-Hispanic blacks, increasing from 3.0 to 7.5 per 100,000 
      population. Health-care providers should maintain heightened suspicion for 
      coccidioidomycosis in patients who live or have traveled in areas where the 
      disease is endemic and who have signs of ILI, pneumonia, or disseminated 
      infection.
CN  - Centers for Disease Control and Prevention (CDC)
LA  - eng
PT  - Journal Article
PL  - United States
TA  - MMWR Morb Mortal Wkly Rep
JT  - MMWR. Morbidity and mortality weekly report
JID - 7802429
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - California/epidemiology
MH  - Child
MH  - Child, Preschool
MH  - Coccidioides
MH  - Coccidioidomycosis/*epidemiology
MH  - Female
MH  - Hospitalization/*statistics & numerical data/trends
MH  - Humans
MH  - Incidence
MH  - Infant
MH  - Male
MH  - Middle Aged
FIR - Bissell, S R
IR  - Bissell SR
FIR - Weiss, E C
IR  - Weiss EC
EDAT- 2009/02/14 09:00
MHDA- 2009/02/20 09:00
CRDT- 2009/02/14 09:00
PHST- 2009/02/14 09:00 [entrez]
PHST- 2009/02/14 09:00 [pubmed]
PHST- 2009/02/20 09:00 [medline]
AID - mm5805a1 [pii]
PST - ppublish
SO  - MMWR Morb Mortal Wkly Rep. 2009 Feb 13;58(5):105-9.