PMID- 19216272
OWN - NLM
STAT- MEDLINE
DCOM- 20090601
LR  - 20131121
IS  - 0882-2786 (Print)
IS  - 0882-2786 (Linking)
VI  - 23
IP  - 6
DP  - 2008 Nov-Dec
TI  - Biomechanical comparison of different surface modifications for dental implants.
PG  - 1037-46
AB  - PURPOSE: A satisfactory clinical outcome in dental implant treatment relies on 
      primary stability for immediate load bearing. While the geometric design of an 
      implant contributes to mechanical stability, the nature of the implant surface 
      itself is also critically important. Biomechanical and microcomputerized 
      tomographic evaluation of implant osseointegration was performed to compare 
      alternative structural, chemical and biochemical, and/or pharmaceutical surface 
      treatments applied to an identical established implant design. MATERIALS AND 
      METHODS: Dental implants with the same geometry but with 6 different surface 
      treatments were tested in vivo in a sheep model (pelvis). Peri-implant bone 
      density and removal torque were compared at 2, 4, and 8 weeks after implantation. 
      Implant surfaces tested were: sandblasted and acid-etched titanium (Ti), 
      sandblasted and etched zirconia, Ti coated with calcium phosphate (CaP), Ti 
      modified via anodic plasma-chemical treatment (APC), bisphosphonate-coated Ti (Ti 
      + Bisphos), and Ti coated with collagen containing chondroitin sulfate (CS). 
      RESULTS: All dental implants were well integrated at the time of sacrifice. There 
      were no significant differences observed in peri-implant bone density between 
      implant groups. After 8 weeks of healing, removal torque values for Ti, Ti + CaP, 
      Ti + Bisphos, and Ti + collagen + CS were significantly higher than those for 
      zirconia and Ti + APC. CONCLUSIONS: Whereas the sandblasted/acid-etched Ti 
      implant can still be considered the reference standard surface for dental 
      implants, functional surface modifications such as bisphosphonate or collagen 
      coating seem to enhance early peri-implant bone formation and should be studied 
      further.
FAU - Ferguson, Stephen J
AU  - Ferguson SJ
AD  - Institute for Surgical Technology and Biomechanics, University of Bern, 
      Switzerland. stephen.ferguson@artorg.unibe.ch
FAU - Langhoff, Jens D
AU  - Langhoff JD
FAU - Voelter, Katrin
AU  - Voelter K
FAU - von Rechenberg, Brigitte
AU  - von Rechenberg B
FAU - Scharnweber, Dieter
AU  - Scharnweber D
FAU - Bierbaum, Susanne
AU  - Bierbaum S
FAU - Schnabelrauch, Matthias
AU  - Schnabelrauch M
FAU - Kautz, Armin R
AU  - Kautz AR
FAU - Frauchiger, Vinzenz M
AU  - Frauchiger VM
FAU - Mueller, Thomas L
AU  - Mueller TL
FAU - van Lenthe, G Harry
AU  - van Lenthe GH
FAU - Schlottig, Falko
AU  - Schlottig F
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Int J Oral Maxillofac Implants
JT  - The International journal of oral & maxillofacial implants
JID - 8611905
RN  - 0 (Bone Density Conservation Agents)
RN  - 0 (Calcium Phosphates)
RN  - 0 (Coated Materials, Biocompatible)
RN  - 0 (Dental Implants)
RN  - 0 (Dental Materials)
RN  - 0 (Diphosphonates)
RN  - 9007-28-7 (Chondroitin Sulfates)
RN  - 9007-34-5 (Collagen)
RN  - 97Z1WI3NDX (calcium phosphate)
RN  - C6V6S92N3C (Zirconium)
RN  - D1JT611TNE (Titanium)
RN  - S38N85C5G0 (zirconium oxide)
SB  - IM
MH  - Acid Etching, Dental/methods
MH  - Animals
MH  - Biomechanical Phenomena
MH  - Bone Density/physiology
MH  - Bone Density Conservation Agents/chemistry
MH  - Calcium Phosphates/chemistry
MH  - Chondroitin Sulfates/chemistry
MH  - Coated Materials, Biocompatible/chemistry
MH  - Collagen/chemistry
MH  - Dental Etching/methods
MH  - *Dental Implants
MH  - Dental Materials/chemistry
MH  - *Dental Prosthesis Design
MH  - Dental Prosthesis Retention
MH  - Diphosphonates/chemistry
MH  - Electrochemical Techniques
MH  - Ilium/surgery
MH  - Materials Testing
MH  - Osseointegration/physiology
MH  - Osteogenesis/physiology
MH  - Random Allocation
MH  - Sheep
MH  - Stress, Mechanical
MH  - Surface Properties
MH  - Time Factors
MH  - Titanium/chemistry
MH  - Torque
MH  - X-Ray Microtomography
MH  - Zirconium/chemistry
EDAT- 2009/02/17 09:00
MHDA- 2009/06/02 09:00
CRDT- 2009/02/17 09:00
PHST- 2009/02/17 09:00 [entrez]
PHST- 2009/02/17 09:00 [pubmed]
PHST- 2009/06/02 09:00 [medline]
PST - ppublish
SO  - Int J Oral Maxillofac Implants. 2008 Nov-Dec;23(6):1037-46.