PMID- 19218118
OWN - NLM
STAT- MEDLINE
DCOM- 20100429
LR  - 20131121
IS  - 1673-4254 (Print)
IS  - 1673-4254 (Linking)
VI  - 29
IP  - 1
DP  - 2009 Jan
TI  - [Interface shear stress between the artificial bones and injectable calcium 
      phosphate glue: an experimental study in rabbits].
PG  - 78-81
AB  - OBJECTIVE: To evaluate the effect of the composite bone material, fibrin glue 
      (FG) combined with beta-tricalcium phosphate (beta-TCP)/monocalcium phosphate, in 
      repairing bone defects and assess the feasibility of using this cement for 
      artificial joint fixation. METHODS: Bone defects were induced in 16 normal adult 
      New Zealand white rabbits at the bilateral femoral lateral condyles where an 
      8-mm-deep hole (4 mm in diameter) was drilled on each side. The composite 
      FG/calcium phosphate cement (CPC) (solution: power volume ratio of 0.3:1) was 
      injected on one side of the bone defects (experimental group) and pressurized for 
      10 minutes, and CPC was injected on the other side (control). The rabbits were 
      sacrificed at 2, 4, 8 or 12 weeks after the operation for gross observation and 
      biomechanical tests. RESULT: The composite material FG/CPC was more effective 
      than CPC for bone defect repair, and biomechanical tests revealed significant 
      differences between them (P<0.05). The shear stress of the artificial bone cement 
      in the FG/CPC group was stronger than that in CPC group. CONCLUSION: The FG/CPC 
      composite possesses good biocompatibility and osteoconductivity and may serve as 
      an ideal material for repairing bone defects.
FAU - Zhao, Liang
AU  - Zhao L
AD  - Department of Orthopaedics, Zhujiang Hospital, Southern Medical University, 
      Guangzhou 510282, China. Zhaoliang711@yahoo.cn
FAU - Li, Qi
AU  - Li Q
FAU - Lin, Li-jun
AU  - Lin LJ
FAU - Zhang, Li
AU  - Zhang L
FAU - Liu, Cheng-long
AU  - Liu CL
FAU - Ding, Chao
AU  - Ding C
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Nan Fang Yi Ke Da Xue Xue Bao
JT  - Nan fang yi ke da xue xue bao = Journal of Southern Medical University
JID - 101266132
RN  - 0 (Biocompatible Materials)
RN  - 0 (Bone Substitutes)
RN  - 0 (Calcium Phosphates)
RN  - 0 (Fibrin Tissue Adhesive)
RN  - 0 (beta-tricalcium phosphate)
RN  - 701EKV9RMN (calcium phosphate, monobasic, anhydrous)
SB  - IM
MH  - Animals
MH  - Biocompatible Materials/chemistry
MH  - Biomechanical Phenomena
MH  - Bone Substitutes/*chemistry
MH  - Calcium Phosphates/*chemistry
MH  - Female
MH  - Fibrin Tissue Adhesive/*chemistry
MH  - *Implants, Experimental
MH  - Male
MH  - Rabbits
MH  - Random Allocation
MH  - Shear Strength
MH  - Tissue Engineering/methods
EDAT- 2009/02/17 09:00
MHDA- 2010/04/30 06:00
CRDT- 2009/02/17 09:00
PHST- 2009/02/17 09:00 [entrez]
PHST- 2009/02/17 09:00 [pubmed]
PHST- 2010/04/30 06:00 [medline]
PST - ppublish
SO  - Nan Fang Yi Ke Da Xue Xue Bao. 2009 Jan;29(1):78-81.