PMID- 19218915
OWN - NLM
STAT- MEDLINE
DCOM- 20090814
LR  - 20151119
IS  - 0392-0488 (Print)
IS  - 0392-0488 (Linking)
VI  - 144
IP  - 1
DP  - 2009 Feb
TI  - Erlotinib-induced pustular eruption.
PG  - 93-6
AB  - The epidermal growth factor receptor (EGFR) inhibitor erlotinib was found to 
      significantly improve overall survival, time to progression, and cancer-related 
      symptoms in locally advanced or metastatic non small cell lung carcinoma (NSCLC). 
      Unfortunately, cutaneous side effects are not rare, the most common one being a 
      follicular acneiform eruption. As it has been observed a positive correlation 
      between rash severity and objective tumor response, it is critical for 
      dermatologists early distinguish it from rashes carrying a different prognosis 
      and needing a different management.
FAU - Cusano, F
AU  - Cusano F
AD  - Unit of Dermatology, G. Rummo Hospital, Benevento, Italy. 
      francesco.cusano2@tin.it
FAU - Ferrara, G
AU  - Ferrara G
FAU - Barletta, E
AU  - Barletta E
FAU - Ingordo, V
AU  - Ingordo V
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Italy
TA  - G Ital Dermatol Venereol
JT  - Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa 
      italiana di dermatologia e sifilografia
JID - 8102852
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Gels)
RN  - 0 (Protein Kinase Inhibitors)
RN  - 0 (Quinazolines)
RN  - 63937KV33D (Erythromycin)
RN  - DA87705X9K (Erlotinib Hydrochloride)
SB  - IM
MH  - Acneiform Eruptions/*chemically induced/drug therapy
MH  - Administration, Cutaneous
MH  - Anti-Bacterial Agents/therapeutic use
MH  - Carcinoma, Non-Small-Cell Lung/*drug therapy/pathology
MH  - Erlotinib Hydrochloride
MH  - Erythromycin/therapeutic use
MH  - Gels
MH  - Humans
MH  - Lung Neoplasms/*drug therapy/pathology
MH  - Male
MH  - Middle Aged
MH  - Protein Kinase Inhibitors/administration & dosage/*adverse effects
MH  - Quinazolines/administration & dosage/*adverse effects
MH  - Treatment Outcome
EDAT- 2009/02/17 09:00
MHDA- 2009/08/15 09:00
CRDT- 2009/02/17 09:00
PHST- 2009/02/17 09:00 [entrez]
PHST- 2009/02/17 09:00 [pubmed]
PHST- 2009/08/15 09:00 [medline]
PST - ppublish
SO  - G Ital Dermatol Venereol. 2009 Feb;144(1):93-6.