PMID- 19221668
OWN - NLM
STAT- MEDLINE
DCOM- 20090421
LR  - 20200825
IS  - 2972-4066 (Electronic)
IS  - 0304-4602 (Linking)
VI  - 38
IP  - 1
DP  - 2009 Jan
TI  - The relevance of the metabolic syndrome.
PG  - 29-5
AB  - INTRODUCTION: To review the definitions of the metabolic syndrome according to 
      various expert groups and assess their relevance to clinical practice. MATERIALS 
      AND METHODS: Medline searches were conducted to identify studies which addressed: 
      (i) the utility of the metabolic syndrome compared to multivariable predictive 
      functions for the identification of individuals at high risk of type 2 diabetes 
      mellitus (T2DM) and cardiovascular disease (CVD), (ii) the importance and 
      definition of obesity in the definition of the metabolic syndrome and (iii) the 
      impact of lifestyle and pharmacological interventions designed to reduce the risk 
      of cardiovascular disease in those with and without the metabolic syndrome. 
      RESULTS: Although inferior to multivariable risk scores in predicting T2DM and 
      CVD, the metabolic syndrome represents a simple clinical tool, particularly for 
      the prediction of T2DM. Obesity is not a critical component of the metabolic 
      syndrome for identifying those at increased risk of CVD but may be important for 
      predicting T2DM. If anything, pharmacological therapy, especially lipid lowering 
      is as, if not more, effective in those with the metabolic syndrome than in those 
      without. CONCLUSIONS: Although the metabolic syndrome appears to have limited 
      utility for the identification of individuals at increased risk of T2DM or CVD, 
      the diagnosis of the metabolic syndrome presents an opportunity to rationalise 
      health services to deliver coordinated care to those with metabolic syndrome.
FAU - Taslim, Siska
AU  - Taslim S
AD  - Department of Endocrinology, Singapore General Hospital, Singapore.
FAU - Tai, E Shyong
AU  - Tai ES
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Singapore
TA  - Ann Acad Med Singap
JT  - Annals of the Academy of Medicine, Singapore
JID - 7503289
SB  - IM
MH  - Cardiovascular Diseases/etiology
MH  - Diabetes Mellitus, Type 2/etiology
MH  - Humans
MH  - Metabolic Syndrome/complications/*diagnosis
MH  - Obesity/complications
RF  - 35
EDAT- 2009/02/18 09:00
MHDA- 2009/04/22 09:00
CRDT- 2009/02/18 09:00
PHST- 2009/02/18 09:00 [entrez]
PHST- 2009/02/18 09:00 [pubmed]
PHST- 2009/04/22 09:00 [medline]
PST - ppublish
SO  - Ann Acad Med Singap. 2009 Jan;38(1):29-5.