PMID- 19225990
OWN - NLM
STAT- MEDLINE
DCOM- 20100319
LR  - 20161125
IS  - 1814-1412 (Electronic)
IS  - 1562-2975 (Linking)
VI  - 10
IP  - 4 Pt 3
DP  - 2009
TI  - A case of late-onset Tourette's disorder successfully treated with aripiprazole: 
      view from blood levels of catecholamine metabolites and brain-derived 
      neurotrophic factor (BDNF).
PG  - 977-80
LID - 10.1080/15622970902718147 [doi]
AB  - We reported a case with late-onset Tourette's disorder (TD) in whom motor tics 
      and emotional instability improved with 18 mg/day of aripiprazole treatment. 
      Plasma HVA levels, but not MHPG levels, were altered during the treatment. In 
      contrast, serum BDNF levels remained consistently low during the treatment 
      course. The present case suggests that aripiprazole might ameliorate tics and 
      emotional instability via influencing dopaminergic neurons in late-onset TD.
FAU - Ikenouchi-Sugita, Atsuko
AU  - Ikenouchi-Sugita A
AD  - Department of Psychiatry, University of Occupational and Environmental Health, 
      School of Medicine, Kitakyushu, Japan. atsuko-i@med.uoeh-u.ac.jp
FAU - Yoshimura, Reiji
AU  - Yoshimura R
FAU - Hayashi, Kenji
AU  - Hayashi K
FAU - Ueda, Nobuhisa
AU  - Ueda N
FAU - Umene-Nakano, Wakako
AU  - Umene-Nakano W
FAU - Hori, Hikaru
AU  - Hori H
FAU - Nakamura, Jun
AU  - Nakamura J
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - World J Biol Psychiatry
JT  - The world journal of biological psychiatry : the official journal of the World 
      Federation of Societies of Biological Psychiatry
JID - 101120023
RN  - 0 (Antipsychotic Agents)
RN  - 0 (Brain-Derived Neurotrophic Factor)
RN  - 0 (Catecholamines)
RN  - 0 (Piperazines)
RN  - 0 (Quinolones)
RN  - 82VFR53I78 (Aripiprazole)
SB  - IM
MH  - Age Factors
MH  - Antipsychotic Agents/*therapeutic use
MH  - Aripiprazole
MH  - Brain/diagnostic imaging
MH  - Brain-Derived Neurotrophic Factor/*metabolism
MH  - Catecholamines/blood/*metabolism
MH  - Diagnostic and Statistical Manual of Mental Disorders
MH  - Humans
MH  - Male
MH  - Piperazines/*therapeutic use
MH  - Quinolones/*therapeutic use
MH  - Severity of Illness Index
MH  - Tomography, X-Ray Computed
MH  - Tourette Syndrome/diagnosis/*drug therapy
MH  - Young Adult
EDAT- 2009/02/20 09:00
MHDA- 2010/03/20 06:00
CRDT- 2009/02/20 09:00
PHST- 2009/02/20 09:00 [entrez]
PHST- 2009/02/20 09:00 [pubmed]
PHST- 2010/03/20 06:00 [medline]
AID - 908829380 [pii]
AID - 10.1080/15622970902718147 [doi]
PST - ppublish
SO  - World J Biol Psychiatry. 2009;10(4 Pt 3):977-80. doi: 10.1080/15622970902718147.