PMID- 19230556
OWN - NLM
STAT- MEDLINE
DCOM- 20090312
LR  - 20190902
IS  - 0070-217X (Print)
IS  - 0070-217X (Linking)
VI  - 331
DP  - 2009
TI  - TT viruses in animals.
PG  - 35-52
AB  - Infection with TT virus (Torque teno virus, TTV), a small, nonenveloped virus 
      with a circular, single-stranded DNA genome classified in the floating genus 
      Anellovirus, is not restricted to humans. Using highly conserved primers derived 
      from the untranslated region of the human TTV genome, a variety of TTV-like 
      viruses have been found circulating in nonhuman primates such as chimpanzees, 
      macaques, and tamarins. TTV variants in nonhuman primates are species-specific, 
      although some genetic groups of human and chimpanzee TTVs cluster to make 
      human/chimpanzee clades. TTVs from macaques and tamarins are increasingly 
      divergent from TTV variants infecting humans and chimpanzees. TTV-like mini virus 
      (TTMV) infections have also been detected in chimpanzees, with genotypes distinct 
      but interspersed with human TTMV genotypes. Pets are also naturally infected with 
      species-specific TTVs, and several isolates have been found in cats and dogs. In 
      addition, other mammals such as tupaias and pigs have species-specific TTVs: 
      swine TTVs are found among pigs worldwide. The genomic organization and proposed 
      transcriptional profiles of TTVs infecting nonhuman primate and other mammalian 
      species are similar to those of human TTVs, and co-evolution of TTVs with their 
      hosts has been suggested. To date, TTVs infecting nonhuman primates and other 
      mammalian species have been under-examined. It is likely that essentially all 
      animals are naturally infected with species-specific TTVs.
FAU - Okamoto, H
AU  - Okamoto H
AD  - Division of Virology, Department of Infections and Immunity, Jichi Medical 
      University School of Medicine, 3311-1 Yakushiji, Shimotsuke-Shi, Tochigi-Ken 
      329-0498, Japan. hokamoto@jichi.ac.jp
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Germany
TA  - Curr Top Microbiol Immunol
JT  - Current topics in microbiology and immunology
JID - 0110513
RN  - 0 (DNA, Viral)
SB  - IM
MH  - Animals
MH  - Base Sequence
MH  - DNA Virus Infections/*veterinary/*virology
MH  - DNA, Viral/chemistry/genetics
MH  - Genome, Viral
MH  - Humans
MH  - Molecular Sequence Data
MH  - Sequence Alignment
MH  - Torque teno virus/*genetics/isolation & purification
RF  - 67
EDAT- 2009/02/24 09:00
MHDA- 2009/03/13 09:00
CRDT- 2009/02/24 09:00
PHST- 2009/02/24 09:00 [entrez]
PHST- 2009/02/24 09:00 [pubmed]
PHST- 2009/03/13 09:00 [medline]
AID - 10.1007/978-3-540-70972-5_3 [doi]
PST - ppublish
SO  - Curr Top Microbiol Immunol. 2009;331:35-52. doi: 10.1007/978-3-540-70972-5_3.