PMID- 19231380 OWN - NLM STAT- MEDLINE DCOM- 20090320 LR - 20090223 IS - 1552-6259 (Electronic) IS - 0003-4975 (Linking) VI - 87 IP - 3 DP - 2009 Mar TI - Valve repair with autologous pericardium for organic lesions in rheumatic tricuspid valve disease. PG - 726-30 LID - 10.1016/j.athoracsur.2008.12.005 [doi] AB - BACKGROUND: Surgical repair of pathologic tricuspid valve disease often fails because of severe anatomic distortion of the valve apparatus, particularly in patients with rheumatic heart disease. This usually leads to tricuspid valve replacement despite the associated prosthesis-related complications. This study examines our experience of tricuspid valve repair with autologous pericardium for organic rheumatic tricuspid valve disease. METHODS: From 1996 to 2007, 31 patients underwent repairs for rheumatic tricuspid valve disease characterized by retracted leaflets and inadequate leaflet area. The patients, aged 14 to 56 years, had a mean New York Heart Association (NYHA) class of 2.9 +/- 0.6. All patients presented with severe tricuspid regurgitation and coexisting left-sided heart valve disease. Glutaraldehyde-treated autologous pericardial patch was used to augment tricuspid valve leaflets. Other techniques were applied as needed, including commissurotomy, leaflet mobilization, annuloplasty, and prosthetic ring implantation. Concomitant operations included left-sided valve replacement in all, and left atrial thrombus removal in 3 patients. Follow-up duration was 4 to 126 months. RESULTS: No deaths or late reoperations occurred. All patients demonstrated clinical improvements on follow-up. Echocardiographic studies before hospital discharge showed less than mild tricuspid regurgitation in all patients. The most recent echocardiographic follow-up showed no tricuspid regurgitation in 10 patients (32.3%), trivial regurgitation in 12 (38.7%), mild regurgitation in 8 (25.8%), and moderate regurgitation in 1 (3.2%). CONCLUSIONS: In selected patients, organic rheumatic tricuspid valve disease can be treated with pericardial patch to augment the retracted leaflets in combination with other techniques. Follow-up reveals excellent tricuspid valve function. FAU - Tang, Hao AU - Tang H AD - Department of Cardiothoracic Surgery, Changhai Hospital, Shanghai, China. FAU - Xu, Zhiyun AU - Xu Z FAU - Zou, Liangjian AU - Zou L FAU - Han, Lin AU - Han L FAU - Lu, Fanglin AU - Lu F FAU - Lang, Xilong AU - Lang X FAU - Song, Zhigang AU - Song Z LA - eng PT - Journal Article PL - Netherlands TA - Ann Thorac Surg JT - The Annals of thoracic surgery JID - 15030100R SB - IM MH - Adolescent MH - Adult MH - Cardiac Surgical Procedures/methods MH - Female MH - Heart Valve Diseases/*surgery MH - Humans MH - Male MH - Middle Aged MH - Pericardium/*transplantation MH - Rheumatic Heart Disease/*surgery MH - Tricuspid Valve/*surgery MH - Young Adult EDAT- 2009/02/24 09:00 MHDA- 2009/03/21 09:00 CRDT- 2009/02/24 09:00 PHST- 2008/09/16 00:00 [received] PHST- 2008/11/29 00:00 [revised] PHST- 2008/12/01 00:00 [accepted] PHST- 2009/02/24 09:00 [entrez] PHST- 2009/02/24 09:00 [pubmed] PHST- 2009/03/21 09:00 [medline] AID - S0003-4975(08)02547-2 [pii] AID - 10.1016/j.athoracsur.2008.12.005 [doi] PST - ppublish SO - Ann Thorac Surg. 2009 Mar;87(3):726-30. doi: 10.1016/j.athoracsur.2008.12.005.