PMID- 19240087
OWN - NLM
STAT- MEDLINE
DCOM- 20100426
LR  - 20131121
IS  - 1461-7285 (Electronic)
IS  - 0269-8811 (Linking)
VI  - 24
IP  - 2
DP  - 2010 Feb
TI  - Lhermitte's sign, electric shock sensations and high dose ecstasy consumption: 
      preliminary findings.
PG  - 213-20
LID - 10.1177/0269881108100528 [doi]
AB  - The objectives of this study were to perform a preliminary investigation into the 
      nature of electric shock-like experiences reported in association with the use of 
      ecstasy tablets thought to contain methylenedioxymethamphetamines (MDMA). This 
      included exploration of reports of electric shock-like experiences from the 
      user's perspectives and identification of other variables that may be associated 
      with their development. Furthermore we aimed to examine whether the 
      well-recognised electric shock-like symptom, Lhermitte's sign (LS), is associated 
      with ecstasy tablet use in some drug users. A single measure, cross-sectional 
      survey was used incorporating mixed qualitative and quantitative methodology. A 
      select group of ecstasy users (n = 35) recruited through a dance, music and 
      lifestyle magazine completed a telephone interview. Lifetime prevalence of LS in 
      the study population was 18% (n = 6). Development of LS was associated with use 
      of more ecstasy tablets before a typical incident. This study indicates a 
      relationship may exist between the use of ecstasy tablets and LS. The 
      relationship may be dose dependent. The majority of the study population used 
      other substances including alcohol when experiencing electrical shock sensations. 
      LS may explain only a proportion of all electrical shock experiences among 
      ecstasy users.
FAU - Boland, B
AU  - Boland B
AD  - Hertfordshire Partnership Foundation Trust, St Albans, Hertfordshire, UK. 
      billy.boland@hertspartsft.nhs.uk
FAU - Mitcheson, L
AU  - Mitcheson L
FAU - Wolff, K
AU  - Wolff K
LA  - eng
PT  - Journal Article
DEP - 20090224
PL  - United States
TA  - J Psychopharmacol
JT  - Journal of psychopharmacology (Oxford, England)
JID - 8907828
RN  - 0 (Hallucinogens)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Adult
MH  - Cross-Sectional Studies
MH  - Data Collection
MH  - Dose-Response Relationship, Drug
MH  - Female
MH  - Hallucinogens/administration & dosage/*toxicity
MH  - Humans
MH  - Male
MH  - N-Methyl-3,4-methylenedioxyamphetamine/administration & dosage/*toxicity
MH  - Young Adult
EDAT- 2009/02/26 09:00
MHDA- 2010/04/27 06:00
CRDT- 2009/02/26 09:00
PHST- 2009/02/26 09:00 [entrez]
PHST- 2009/02/26 09:00 [pubmed]
PHST- 2010/04/27 06:00 [medline]
AID - 0269881108100528 [pii]
AID - 10.1177/0269881108100528 [doi]
PST - ppublish
SO  - J Psychopharmacol. 2010 Feb;24(2):213-20. doi: 10.1177/0269881108100528. Epub 
      2009 Feb 24.