PMID- 19240137
OWN - NLM
STAT- MEDLINE
DCOM- 20100104
LR  - 20220317
IS  - 1460-2199 (Electronic)
IS  - 1047-3211 (Print)
IS  - 1047-3211 (Linking)
VI  - 19
IP  - 11
DP  - 2009 Nov
TI  - The neural architecture of music-evoked autobiographical memories.
PG  - 2579-94
LID - 10.1093/cercor/bhp008 [doi]
AB  - The medial prefrontal cortex (MPFC) is regarded as a region of the brain that 
      supports self-referential processes, including the integration of sensory 
      information with self-knowledge and the retrieval of autobiographical 
      information. I used functional magnetic resonance imaging and a novel procedure 
      for eliciting autobiographical memories with excerpts of popular music dating to 
      one's extended childhood to test the hypothesis that music and autobiographical 
      memories are integrated in the MPFC. Dorsal regions of the MPFC (Brodmann area 
      8/9) were shown to respond parametrically to the degree of autobiographical 
      salience experienced over the course of individual 30 s excerpts. Moreover, the 
      dorsal MPFC also responded on a second, faster timescale corresponding to the 
      signature movements of the musical excerpts through tonal space. These results 
      suggest that the dorsal MPFC associates music and memories when we experience 
      emotionally salient episodic memories that are triggered by familiar songs from 
      our personal past. MPFC acted in concert with lateral prefrontal and posterior 
      cortices both in terms of tonality tracking and overall responsiveness to 
      familiar and autobiographically salient songs. These findings extend the results 
      of previous autobiographical memory research by demonstrating the spontaneous 
      activation of an autobiographical memory network in a naturalistic task with low 
      retrieval demands.
FAU - Janata, Petr
AU  - Janata P
AD  - Department of Psychology, Center for Mind and Brain, University of California, 
      Davis, CA 95618, USA.
LA  - eng
GR  - DC05146/DC/NIDCD NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20090224
PL  - United States
TA  - Cereb Cortex
JT  - Cerebral cortex (New York, N.Y. : 1991)
JID - 9110718
SB  - IM
EIN - Cereb Cortex. 2010 Jan;20(1):254-5
MH  - Adolescent
MH  - *Autobiographies as Topic
MH  - *Cues
MH  - Emotions/*physiology
MH  - Evoked Potentials, Auditory/*physiology
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging/methods
MH  - Male
MH  - Memory/physiology
MH  - Mental Recall/*physiology
MH  - *Music
MH  - Prefrontal Cortex/*physiology
MH  - *Self Concept
MH  - Young Adult
PMC - PMC2758676
EDAT- 2009/02/26 09:00
MHDA- 2010/01/05 06:00
PMCR- 2009/02/24
CRDT- 2009/02/26 09:00
PHST- 2009/02/26 09:00 [entrez]
PHST- 2009/02/26 09:00 [pubmed]
PHST- 2010/01/05 06:00 [medline]
PHST- 2009/02/24 00:00 [pmc-release]
AID - bhp008 [pii]
AID - 10.1093/cercor/bhp008 [doi]
PST - ppublish
SO  - Cereb Cortex. 2009 Nov;19(11):2579-94. doi: 10.1093/cercor/bhp008. Epub 2009 Feb 
      24.