PMID- 19253545
OWN - NLM
STAT- MEDLINE
DCOM- 20100617
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 26
IP  - 6
DP  - 2008 Nov
TI  - [Fast determination of polybrominated diphenyl ethers in human milk using gas 
      chromatography-negative chemical ionization/mass spectrometry].
PG  - 687-91
AB  - A method for the quantitative determination of 8 polybrominated diphenyl ethers 
      (PBDEs) in human milk was established using gas chromatography-negative chemical 
      ionization/mass spectrometry (GC-NCI/MS). After extraction by Soxhlet extractor, 
      the lipid in the extract was removed by acidic silica, and the analyte was 
      further purified by the multilayer silica-alumina column. The concentrations of 
      BDE28, BDE47, BDE99, BDE100, BDE153, BDE154, BDE183 and BDE209 in human milk were 
      fast determined by GC-NCI/MS in selected ion monitoring (SIM) mode on a 7 m 
      column. The quantitative analysis was performed by isotope dilution method for 
      BDE209 and internal standard method for other PBDEs. The limits of detection 
      (LODs) of PBDEs in the lipid ranged from 1.74 to 6.35 pg/g. The recoveries of the 
      spiked PBDEs were between 61.5% and 108% and their relative standard deviations 
      (RSDs) (n = 6) were between 2.06% and 10.1%. The method was further validated by 
      the analysis of the reference materials of human milk. It was demonstrated that 
      it is a low cost, rapid and reliable alternative for the trace analysis of 
      selected PBDEs, especially for BDE209 in human milk.
FAU - Liu, Yinping
AU  - Liu Y
AD  - National Institute of Nutrition and Food Safety, Chinese Center for Disease 
      Control and Prevention, Beijing 100050, China. liuyinping0930@163.com
FAU - Dai, Peng
AU  - Dai P
FAU - Li, Jingguang
AU  - Li J
FAU - Zhang, Lei
AU  - Zhang L
FAU - Zhao, Yunfeng
AU  - Zhao Y
FAU - Wu, Yongning
AU  - Wu Y
FAU - Zhu, Lingyan
AU  - Zhu L
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Halogenated Diphenyl Ethers)
SB  - IM
MH  - Analytic Sample Preparation Methods
MH  - Calibration
MH  - Environmental Monitoring/*methods
MH  - Food Analysis/*methods
MH  - Food Contamination/*analysis
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Halogenated Diphenyl Ethers/*analysis
MH  - Humans
MH  - Injections
MH  - Limit of Detection
MH  - Milk, Human/*chemistry
MH  - Reproducibility of Results
MH  - Temperature
MH  - Time Factors
EDAT- 2009/03/04 09:00
MHDA- 2010/06/18 06:00
CRDT- 2009/03/04 09:00
PHST- 2009/03/04 09:00 [entrez]
PHST- 2009/03/04 09:00 [pubmed]
PHST- 2010/06/18 06:00 [medline]
AID - 10.1016/s1872-2059(08)60032-2 [doi]
PST - ppublish
SO  - Se Pu. 2008 Nov;26(6):687-91. doi: 10.1016/s1872-2059(08)60032-2.