PMID- 19259243 OWN - NLM STAT- MEDLINE DCOM- 20090402 LR - 20220309 IS - 1094-4087 (Electronic) IS - 1094-4087 (Linking) VI - 17 IP - 5 DP - 2009 Mar 2 TI - Effect of image quality on tissue thickness measurements obtained with spectral domain-optical coherence tomography. PG - 4019-36 AB - The purpose of this study was to investigate the effect of image quality on retinal nerve fiber layer (RNFL) and retinal thickness measurements obtained using three commercially available spectral domain-optical coherence tomographers (SD-OCT). Subjectively determined good, medium and poor quality images were obtained from four healthy and one glaucoma suspect eyes. RNFL and retinal thickness measurements were compared as a function of image quality. Results indicate that when image quality is within the range specified as acceptable by SD-OCT manufacturers, RNFL and retinal thickness measurements are comparable. FAU - Balasubramanian, Madhusudhanan AU - Balasubramanian M AD - Hamilton Glaucoma Center, Department of Ophthalmology, University of California, San Diego, La Jolla CA. 92093-0946 , USA. FAU - Bowd, Christopher AU - Bowd C FAU - Vizzeri, Gianmarco AU - Vizzeri G FAU - Weinreb, Robert N AU - Weinreb RN FAU - Zangwill, Linda M AU - Zangwill LM LA - eng GR - R01 EY011008/EY/NEI NIH HHS/United States GR - R01 EY011008-13/EY/NEI NIH HHS/United States GR - EY 11008/EY/NEI NIH HHS/United States PT - Comparative Study PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't PL - United States TA - Opt Express JT - Optics express JID - 101137103 SB - IM MH - Adult MH - Glaucoma/*pathology MH - Humans MH - Imaging, Three-Dimensional MH - Middle Aged MH - Nerve Fibers/*pathology MH - Quality Control MH - Retina/*pathology MH - Tomography, Optical Coherence/instrumentation/*methods/standards/statistics & numerical data PMC - PMC2848174 MID - NIHMS150290 EDAT- 2009/03/05 09:00 MHDA- 2009/04/03 09:00 PMCR- 2010/03/31 CRDT- 2009/03/05 09:00 PHST- 2009/03/05 09:00 [entrez] PHST- 2009/03/05 09:00 [pubmed] PHST- 2009/04/03 09:00 [medline] PHST- 2010/03/31 00:00 [pmc-release] AID - 176997 [pii] AID - 10.1364/oe.17.004019 [doi] PST - ppublish SO - Opt Express. 2009 Mar 2;17(5):4019-36. doi: 10.1364/oe.17.004019.