PMID- 19259257
OWN - NLM
STAT- MEDLINE
DCOM- 20090402
LR  - 20220309
IS  - 1094-4087 (Electronic)
IS  - 1094-4087 (Linking)
VI  - 17
IP  - 5
DP  - 2009 Mar 2
TI  - Ultrahigh-resolution versus speckle noise-reduction in spectral-domain optical 
      coherence tomography.
PG  - 4221-35
AB  - Ultrahigh-resolution (UHR) spectral-domain optical coherence tomography (SD-OCT) 
      and speckle noise-reduced SD-OCT instruments were compared with regard to their 
      ability to visualize retinal microstructures and detect micropathologies in the 
      same series of eyes in this hospital-based study. Both the instruments 
      identically visualized normal retinal structures, except for the retinal ganglion 
      cell layer, which was better delineated by the speckle noise-reduced SD-OCT 
      instrument. Retinal pigment epithelium (RPE) and Bruch's membrane were better 
      delineated by UHR SD-OCT. Retinal and sub-RPE pathologies were also identically 
      visualized by both the instruments. Layer differentiation for locating each 
      pathology was better visualized by speckle noise-reduced SD-OCT.
FAU - Hangai, Masanori
AU  - Hangai M
AD  - Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School 
      of Medicine, 54 Kawaharacho, Shougoin, Sakyo-ku, Kyoto 606-8507, Japan. 
      hangai@kuhp.kyoto-u.ac.jp
FAU - Yamamoto, Motoshi
AU  - Yamamoto M
FAU - Sakamoto, Atsushi
AU  - Sakamoto A
FAU - Yoshimura, Nagahisa
AU  - Yoshimura N
LA  - eng
PT  - Comparative Study
PT  - Evaluation Study
PT  - Journal Article
PL  - United States
TA  - Opt Express
JT  - Optics express
JID - 101137103
SB  - IM
MH  - Aged
MH  - Choroidal Neovascularization/pathology
MH  - Diabetic Retinopathy/pathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Retina/anatomy & histology/*pathology
MH  - Retinal Diseases/diagnosis/*pathology
MH  - Retinal Pigment Epithelium/pathology
MH  - Retinitis Pigmentosa/pathology
MH  - Tomography, Optical Coherence/*methods/statistics & numerical data
EDAT- 2009/03/05 09:00
MHDA- 2009/04/03 09:00
CRDT- 2009/03/05 09:00
PHST- 2009/03/05 09:00 [entrez]
PHST- 2009/03/05 09:00 [pubmed]
PHST- 2009/04/03 09:00 [medline]
AID - 177011 [pii]
AID - 10.1364/oe.17.004221 [doi]
PST - ppublish
SO  - Opt Express. 2009 Mar 2;17(5):4221-35. doi: 10.1364/oe.17.004221.