PMID- 19269490 OWN - NLM STAT- MEDLINE DCOM- 20090429 LR - 20191210 IS - 1873-3573 (Electronic) IS - 0039-9140 (Linking) VI - 78 IP - 3 DP - 2009 May 15 TI - Application of ionic liquids in the microwave-assisted extraction of polyphenolic compounds from medicinal plants. PG - 1177-84 LID - 10.1016/j.talanta.2009.01.040 [doi] AB - Ionic liquids (ILs) solutions as solvents were successfully applied in the microwave-assisted extraction (MAE) of polyphenolic compounds from medicinal plants. ILs, its concentration and MAE conditions were investigated in order to extract polyphenolic compounds effectively from Psidium guajava Linn. (P. guajava) leaves and Smilax china (S. china) tubers. The results obtained indicated that the anions and cations of ILs had influences on the extraction of polyphenolic compounds as well as the ILs with electron-rich aromatic pi-system enhanced extraction ability. Under the optimized conditions, the extraction yields of the polyphenolic compounds were in the range of 79.5-93.8% with one-step extraction, and meanwhile the recoveries were in the range of 85.2-103% with relative standard deviations (R.S.D.s) lower than 5.6%. Compared to conventional extraction procedures, the results suggested that the proposed method was effective and alternative for the extraction of polyphenolic compounds from medicinal plants. In addition, the extraction mechanisms and the structures of samples before and after extraction were also investigated. ILs solutions as green solvents in the MAE of polyphenolic compounds from medicinal plant samples showed a great promising prospect. FAU - Du, Fu-You AU - Du FY AD - School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China. FAU - Xiao, Xiao-Hua AU - Xiao XH FAU - Luo, Xue-Jun AU - Luo XJ FAU - Li, Gong-Ke AU - Li GK LA - eng PT - Evaluation Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20090130 PL - Netherlands TA - Talanta JT - Talanta JID - 2984816R RN - 0 (Flavonoids) RN - 0 (Ionic Liquids) RN - 0 (Phenols) RN - 0 (Plant Extracts) RN - 0 (Polyphenols) SB - IM MH - Flavonoids/*isolation & purification MH - Ionic Liquids MH - Methods MH - Microwaves MH - Phenols/*isolation & purification MH - Plant Extracts MH - Plants, Medicinal/*chemistry MH - Polyphenols MH - Psidium/chemistry EDAT- 2009/03/10 09:00 MHDA- 2009/04/30 09:00 CRDT- 2009/03/10 09:00 PHST- 2008/10/12 00:00 [received] PHST- 2009/01/16 00:00 [revised] PHST- 2009/01/20 00:00 [accepted] PHST- 2009/03/10 09:00 [entrez] PHST- 2009/03/10 09:00 [pubmed] PHST- 2009/04/30 09:00 [medline] AID - S0039-9140(09)00101-5 [pii] AID - 10.1016/j.talanta.2009.01.040 [doi] PST - ppublish SO - Talanta. 2009 May 15;78(3):1177-84. doi: 10.1016/j.talanta.2009.01.040. Epub 2009 Jan 30.