PMID- 19280939
OWN - NLM
STAT- MEDLINE
DCOM- 20090519
LR  - 20110727
IS  - 0047-1852 (Print)
IS  - 0047-1852 (Linking)
VI  - 67
IP  - 3
DP  - 2009 Mar
TI  - [Intravenous immunoglobulin (IVIG)].
PG  - 599-605
AB  - Intravenous immunoglobulin (VIG) was given by Imbach in 1981 to idiopathic 
      thrombocytopenic purpura (ITP). The cure of many of the patients in response to 
      the IVIG expanded the use of IVIG to other autoimmune condition. The diseases 
      proven the efficacy of VIG by controlled trial were ITP, Guillain-Barre syndrome, 
      chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), multiple motor 
      neuropathy, multiple sclerosis, myasthenia gravis, ANCA related vasculitis, 
      Kawasaki disease, autoimmune uveitis and dermatomyositis. There are several 
      uncontrolled trials and case reports about the efficacy of IVIG on the connective 
      tissue diseases, such as systemic lupus erythematosus, systemic sclerosis, 
      Sjogren syndrome, antiphospholipid antibody syndrome and Still's disease. In 
      Japan, only ITP, Kawasaki disease and CIDP are allowed to be use IVIG by health 
      insurance. I would like to summarize the application of VIG on collagen diseases 
      and refer both novel mechanisms as well as to complications of this therapy.
FAU - Hara, Masako
AU  - Hara M
AD  - Institute of Rheumatology, Tokyo Women's Medical University.
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PT  - Review
PL  - Japan
TA  - Nihon Rinsho
JT  - Nihon rinsho. Japanese journal of clinical medicine
JID - 0420546
RN  - 0 (Antibodies, Antineutrophil Cytoplasmic)
RN  - 0 (Immunoglobulins, Intravenous)
SB  - IM
MH  - Animals
MH  - Antibodies, Antineutrophil Cytoplasmic
MH  - Collagen Diseases/*drug therapy
MH  - Dermatomyositis/drug therapy
MH  - Humans
MH  - Immunoglobulins, Intravenous/*administration & dosage/adverse 
      effects/pharmacology
MH  - Infusions, Intravenous
MH  - Lupus Erythematosus, Systemic/drug therapy
MH  - Polymyositis/drug therapy
MH  - Scleroderma, Systemic/drug therapy
MH  - Vasculitis/drug therapy
RF  - 16
EDAT- 2009/03/14 09:00
MHDA- 2009/05/20 09:00
CRDT- 2009/03/14 09:00
PHST- 2009/03/14 09:00 [entrez]
PHST- 2009/03/14 09:00 [pubmed]
PHST- 2009/05/20 09:00 [medline]
PST - ppublish
SO  - Nihon Rinsho. 2009 Mar;67(3):599-605.