PMID- 19281743
OWN - NLM
STAT- MEDLINE
DCOM- 20090508
LR  - 20190608
IS  - 0301-0430 (Print)
IS  - 0301-0430 (Linking)
VI  - 71
IP  - 3
DP  - 2009 Mar
TI  - Progressive renal failure as the first manifestation of monoclonal light-chain 
      deposition disease with rapid multiple organ involvement.
PG  - 314-7
AB  - Light-chain deposition disease (LCDD) is an uncommon condition in which 
      monoclonal light chains are deposited in different organs causing varying degrees 
      of tissue damage. We report the case of a 56-year-old male with progressive renal 
      failure as the first manifestation of LCDD without initial evidence of monoclonal 
      immunoglobulin protein in either serum or urine. The patient later developed 
      severe systemic disease with rapid multiple organ involvement. Finally, he died 2 
      months after diagnosis, despite steroid and cyclophosphamide therapy.
FAU - Perez-Suarez, G
AU  - Perez-Suarez G
AD  - Department of Nephrology, Hospital Universitario de Canarias, Tenerife, Spain. 
      gpersuarez@gmail.com
FAU - Raya, J M
AU  - Raya JM
FAU - Alvarez, A
AU  - Alvarez A
FAU - Martin, A
AU  - Martin A
FAU - Alvarez-Arguelles, H
AU  - Alvarez-Arguelles H
FAU - Hernandez-Garcia, M
AU  - Hernandez-Garcia M
FAU - Hernandez, D
AU  - Hernandez D
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Germany
TA  - Clin Nephrol
JT  - Clinical nephrology
JID - 0364441
RN  - 0 (Immunoglobulin Light Chains)
SB  - IM
MH  - Disease Progression
MH  - Fatal Outcome
MH  - Humans
MH  - Immunoglobulin Light Chains/*metabolism
MH  - Male
MH  - Middle Aged
MH  - Multiple Organ Failure/*etiology/metabolism/physiopathology
MH  - Renal Insufficiency/*etiology/metabolism/physiopathology
EDAT- 2009/03/14 09:00
MHDA- 2009/05/09 09:00
CRDT- 2009/03/14 09:00
PHST- 2009/03/14 09:00 [entrez]
PHST- 2009/03/14 09:00 [pubmed]
PHST- 2009/05/09 09:00 [medline]
AID - 5533 [pii]
AID - 10.5414/cnp71314 [doi]
PST - ppublish
SO  - Clin Nephrol. 2009 Mar;71(3):314-7. doi: 10.5414/cnp71314.