PMID- 19300599 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20110517 LR - 20211020 IS - 1176-6328 (Print) IS - 1178-2021 (Electronic) IS - 1176-6328 (Linking) VI - 3 IP - 5 DP - 2007 TI - Increase of plasma brain-derived neurotrophic factor levels in two psychotic depressed patients responding to lithium addition to paroxetine treatment. PG - 683-6 AB - We report two patients with psychotic depression who were successfully treated with a lithium addition to ongoing paroxetine treatment. In both cases, plasma brain-derived neurotrophic factor (BDNF) levels increased about 2-fold after lithium augmentation to paroxetine, compared with paroxetine treatment alone. Plasma paroxetine levels did not change after lithium addition. These results suggest that the increases in plasma BDNF levels reflect recovery from depressive symptoms in psychotic depression. FAU - Yoshimura, Reiji AU - Yoshimura R AD - Department of Psychiatry, University of Occupational and Environmental Health, Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, Japan. FAU - Tsuji, Koshiro AU - Tsuji K FAU - Ueda, Nobuhisa AU - Ueda N FAU - Nakamura, Jun AU - Nakamura J LA - eng PT - Case Reports PL - New Zealand TA - Neuropsychiatr Dis Treat JT - Neuropsychiatric disease and treatment JID - 101240304 PMC - PMC2656306 OTO - NOTNLM OT - brain-derived neurotrophic factor OT - lithium OT - paroxetine OT - psychotic depression EDAT- 2007/10/01 00:00 MHDA- 2007/10/01 00:01 PMCR- 2008/02/01 CRDT- 2009/03/21 09:00 PHST- 2009/03/21 09:00 [entrez] PHST- 2007/10/01 00:00 [pubmed] PHST- 2007/10/01 00:01 [medline] PHST- 2008/02/01 00:00 [pmc-release] AID - ndt-3-683 [pii] PST - ppublish SO - Neuropsychiatr Dis Treat. 2007;3(5):683-6.