PMID- 19317900
OWN - NLM
STAT- MEDLINE
DCOM- 20090715
LR  - 20220316
IS  - 1475-2840 (Electronic)
IS  - 1475-2840 (Linking)
VI  - 8
DP  - 2009 Mar 24
TI  - The impact of diabetes on coronary heart disease differs from that on ischaemic 
      stroke with regard to the gender.
PG  - 17
LID - 10.1186/1475-2840-8-17 [doi]
AB  - BACKGROUND: To study the diabetes related CVD risk between men and women of 
      different ages. METHODS: Hazards ratios (HRs) (95%CI) for acute CHD and ischaemic 
      stroke events were estimated based on data of Finnish and Swedish cohorts of 5111 
      women and 4167 men. RESULTS: 182 (3.6%) women and 348 (8.4%) men had CHD and 129 
      (2.5%) women and 137 (3.3%) men ischaemic stroke events. The multivariate 
      adjusted HRs for acute CHD at age groups of 40-49, 50-59 and 60-69 years were 
      1.00 (1.94), 1.78 (4.23), 3.75 (8.40) in women (men) without diabetes and 4.35 
      (5.40), 5.49 (9.54) and 8.84 (13.76) in women (men) with diabetes. The 
      corresponding HRs for ischaemic stroke were 1.00 (1.26), 2.48 (2.83) and 5.17 
      (5.11) in women (men) without diabetes and 4.14 (4.91), 3.32 (6.75) and 13.91 
      (18.06) in women (men) with diabetes, respectively. CONCLUSION: CHD risk was 
      higher in men than in women but difference reduced in diabetic population. 
      Diabetes, however, increased stroke risk more in men than in women.
FAU - Hyvarinen, Marjukka
AU  - Hyvarinen M
AD  - Department of Public Health, University of Helsinki, Helsinki, Finland. 
      marjukka.hyvarinen@helsinki.fi
FAU - Tuomilehto, Jaakko
AU  - Tuomilehto J
FAU - Laatikainen, Tiina
AU  - Laatikainen T
FAU - Soderberg, Stefan
AU  - Soderberg S
FAU - Eliasson, Mats
AU  - Eliasson M
FAU - Nilsson, Peter
AU  - Nilsson P
FAU - Qiao, Qing
AU  - Qiao Q
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20090324
PL  - England
TA  - Cardiovasc Diabetol
JT  - Cardiovascular diabetology
JID - 101147637
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cohort Studies
MH  - Coronary Disease/epidemiology/*etiology
MH  - Diabetes Complications/epidemiology/*etiology
MH  - Female
MH  - Finland/epidemiology
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
MH  - Sex Characteristics
MH  - Stroke/epidemiology/*etiology
MH  - Sweden/epidemiology
PMC - PMC2679722
EDAT- 2009/03/26 09:00
MHDA- 2009/07/16 09:00
PMCR- 2009/03/24
CRDT- 2009/03/26 09:00
PHST- 2009/02/18 00:00 [received]
PHST- 2009/03/24 00:00 [accepted]
PHST- 2009/03/26 09:00 [entrez]
PHST- 2009/03/26 09:00 [pubmed]
PHST- 2009/07/16 09:00 [medline]
PHST- 2009/03/24 00:00 [pmc-release]
AID - 1475-2840-8-17 [pii]
AID - 10.1186/1475-2840-8-17 [doi]
PST - epublish
SO  - Cardiovasc Diabetol. 2009 Mar 24;8:17. doi: 10.1186/1475-2840-8-17.