PMID- 19319915
OWN - NLM
STAT- MEDLINE
DCOM- 20090608
LR  - 20101118
IS  - 1521-1878 (Electronic)
IS  - 0265-9247 (Linking)
VI  - 31
IP  - 5
DP  - 2009 May
TI  - How did parasitic worms evolve?
PG  - 496-9
LID - 10.1002/bies.200900010 [doi]
AB  - Nematodes are important parasites of humans and other animals. Nematode 
      parasitism is thought to have evolved by free-living, facultatively developing, 
      arrested larvae becoming associated with animals, ultimately becoming parasites. 
      The formation of free-living arrested larvae of the nematode Caenorhabditis 
      elegans is controlled by the environment, and involves dafachronic acid (DA) and 
      transforming growth factor (TGF)-beta signalling. Recent data have shown that DA 
      acid signalling plays a conserved role in controlling larval development in both 
      free-living and parasitic species. In contrast, TGF-beta signalling does not seem 
      to be conserved; this difference perhaps points to how nematode parasitism did 
      evolve.
FAU - Viney, Mark E
AU  - Viney ME
AD  - School of Biological Sciences, University of Bristol, Bristol, UK.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Bioessays
JT  - BioEssays : news and reviews in molecular, cellular and developmental biology
JID - 8510851
RN  - 0 (Cholestenes)
RN  - 0 (Transforming Growth Factor beta)
RN  - 0 (dafachronic acid)
SB  - IM
MH  - Animals
MH  - *Biological Evolution
MH  - Caenorhabditis elegans/growth & development/metabolism/physiology
MH  - Cholestenes/metabolism
MH  - Environment
MH  - Host-Parasite Interactions/*physiology
MH  - Humans
MH  - Nematoda/growth & development/metabolism/*physiology
MH  - Transforming Growth Factor beta/metabolism
EDAT- 2009/03/26 09:00
MHDA- 2009/06/09 09:00
CRDT- 2009/03/26 09:00
PHST- 2009/03/26 09:00 [entrez]
PHST- 2009/03/26 09:00 [pubmed]
PHST- 2009/06/09 09:00 [medline]
AID - 10.1002/bies.200900010 [doi]
PST - ppublish
SO  - Bioessays. 2009 May;31(5):496-9. doi: 10.1002/bies.200900010.