PMID- 193294 OWN - NLM STAT- MEDLINE DCOM- 19770622 LR - 20061115 IS - 0507-3758 (Print) IS - 0507-3758 (Linking) VI - 23 IP - 1 DP - 1977 Jan TI - [Hexokinase activity in blood serum during carcinogenesis]. PG - 45-8 AB - During carcinogenesis, induced by diethylnitrosamine in rats Wistar (in doses of 2.5 mg per Kg of weight daily with drinking water), the hexokinase (HK) activity in blood serum was observed with the appearance of the first morphological symptoms of tumor growth. It is observed mainly starting from the first months. At the end of the experimental period (8-9th month), when hepatomas develop in the liver, the HK activity in blood serum was noted almost in all cases. No serum HK activity was found in control rats. FAU - Kil'dema, L A AU - Kil'dema LA LA - rus PT - English Abstract PT - Journal Article TT - Ob aktivnosti geksokinazy v syrovotke krovi pri kantserogeneze. PL - Russia (Federation) TA - Vopr Onkol JT - Voprosy onkologii JID - 0413775 RN - EC 2.7.1.1 (Hexokinase) SB - IM MH - Animals MH - Carcinoma, Hepatocellular/*enzymology MH - Hexokinase/*blood MH - Liver Neoplasms/*enzymology MH - Male MH - Neoplasms, Experimental/enzymology MH - Rats EDAT- 1977/01/01 00:00 MHDA- 1977/01/01 00:01 CRDT- 1977/01/01 00:00 PHST- 1977/01/01 00:00 [pubmed] PHST- 1977/01/01 00:01 [medline] PHST- 1977/01/01 00:00 [entrez] PST - ppublish SO - Vopr Onkol. 1977 Jan;23(1):45-8.