PMID- 19337388
OWN - NLM
STAT- MEDLINE
DCOM- 20090729
LR  - 20211020
IS  - 1928-9022 (Electronic)
IS  - 0830-9000 (Print)
IS  - 0830-9000 (Linking)
VI  - 73
IP  - 1
DP  - 2009 Jan
TI  - Evaluation of transpulmonary thermodilution as a method to measure cardiac output 
      in anesthetized cats.
PG  - 1-6
AB  - The objectives of this study were to evaluate the use of a transpulmonary 
      thermodilution (Trans) technique for the measurement of cardiac output, and to 
      determine the agreement between Trans and conventional thermodilution (TD) in 
      anesthetized cats. Using each technique, cardiac output was measured in 5 mature 
      cats (weights 2.4 to 5.6 kg) anesthetized with isoflurane. To induce different 
      levels of cardiac output in each cat, anesthesia was maintained at > 1.5x 
      end-tidal minimum alveolar concentration (MAC) of isoflurane, and at 1.3x 
      end-tidal isoflurane MAC with and without administration of dobutamine. At least 
      2 comparisons between TD and Trans values were made at each cardiac output rate. 
      Thirty-two of the 42 recorded comparisons were analyzed. Linear regression 
      analysis (TD vs Trans) yielded an r(2) value of 0.83. The mean bias (TD-Trans) 
      was -3.7 mL/kg/min with limits of agreement of -35.9 to 28.5 mL/kg/min. The 
      concordance coefficient was 0.91. The Trans method showed good relationship and 
      good agreement with TD in anesthetized cats. The Trans method is a relatively 
      noninvasive, practical, and safe method to measure cardiac output in anesthetized 
      cats.
FAU - Beaulieu, Kim E
AU  - Beaulieu KE
AD  - Department of Clinical Studies, Ontario Veterinary College, University of Guelph, 
      Ontario, Canada. kim.beaulieu@kkh.unib.ch
FAU - Kerr, Carolyn L
AU  - Kerr CL
FAU - McDonell, Wayne N
AU  - McDonell WN
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Canada
TA  - Can J Vet Res
JT  - Canadian journal of veterinary research = Revue canadienne de recherche 
      veterinaire
JID - 8607793
SB  - IM
MH  - Animals
MH  - Cardiac Output/*physiology
MH  - Cats/*physiology
MH  - Humans
MH  - Intubation/methods/veterinary
MH  - Pulmonary Circulation/*physiology
MH  - Regression Analysis
MH  - Reproducibility of Results
MH  - Thermodilution/instrumentation/methods/*veterinary
PMC - PMC2613590
EDAT- 2009/04/02 09:00
MHDA- 2009/07/30 09:00
PMCR- 2009/04/01
CRDT- 2009/04/02 09:00
PHST- 2007/04/10 00:00 [received]
PHST- 2008/02/12 00:00 [accepted]
PHST- 2009/04/02 09:00 [entrez]
PHST- 2009/04/02 09:00 [pubmed]
PHST- 2009/07/30 09:00 [medline]
PHST- 2009/04/01 00:00 [pmc-release]
AID - cjvr_73_1 [pii]
PST - ppublish
SO  - Can J Vet Res. 2009 Jan;73(1):1-6.