PMID- 19339343
OWN - NLM
STAT- MEDLINE
DCOM- 20110728
LR  - 20090527
IS  - 1471-8405 (Electronic)
IS  - 0962-7480 (Linking)
VI  - 59
IP  - 4
DP  - 2009 Jun
TI  - Occupational allergy to Artemia fish fry feed in aquaculture.
PG  - 243-8
LID - 10.1093/occmed/kqp041 [doi]
AB  - BACKGROUND: Artemia (brine shrimp) is used as feed for fish fry and shrimp in 
      aquaculture. Two employees in a Norwegian aquaculture research farm reported 
      having chest symptoms when working in an Artemia hatch room. AIMS: To determine 
      the presence and prevalence of Artemia sensitization at the farm and the extent 
      of any Artemia-related respiratory and hand skin symptoms and to identify the 
      allergens involved. METHODS: Participants completed a questionnaire and 
      structured interview. Skin prick tests (SPTs) were performed, and immunoglobulin 
      E (IgE) antibodies to Artemia, shrimp and recombinant tropomyosin were 
      determined. Gel electrophoresis and immunoblots of Artemia extracts were also 
      carried out. RESULTS: Thirty of 42 employees (71%) participated. Among the 24 
      subjects exposed to Artemia, four (17%) reported chest and/or hand skin symptoms 
      during exposure and three of them were IgE sensitized to Artemia. Five (21%) of 
      those exposed demonstrated IgE antibodies to Artemia and four (17%) had 
      immediate-positive SPTs. A serum pool from these subjects exhibited IgE binding 
      to a protein of approximately 97 kDa in the Artemia extract. CONCLUSIONS: 
      Occupational exposure to the Artemia fish fry feed can cause IgE sensitization 
      and allergic symptoms affecting airways and skin.
FAU - Granslo, Jens-Tore
AU  - Granslo JT
AD  - Department of Occupational Medicine, Haukeland University Hospital, Bergen, 
      Norway. jens-tore.granslo@helse-bergen.no
FAU - Van Do, Thien
AU  - Van Do T
FAU - Aasen, Tor B
AU  - Aasen TB
FAU - Irgens, Agot
AU  - Irgens A
FAU - Florvaag, Erik
AU  - Florvaag E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20090401
PL  - England
TA  - Occup Med (Lond)
JT  - Occupational medicine (Oxford, England)
JID - 9205857
RN  - 0 (Recombinant Proteins)
RN  - 0 (Tropomyosin)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adult
MH  - Animals
MH  - *Aquaculture
MH  - *Artemia
MH  - Asthma/epidemiology/immunology
MH  - Cross-Sectional Studies
MH  - Dermatitis, Occupational/epidemiology/immunology
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Hand Dermatoses/diagnosis/epidemiology/immunology
MH  - Humans
MH  - Hypersensitivity, Immediate/diagnosis/*epidemiology/immunology
MH  - Immunoglobulin E/metabolism
MH  - Male
MH  - Middle Aged
MH  - Occupational Diseases/diagnosis/*epidemiology/immunology
MH  - Occupational Exposure/*adverse effects
MH  - Recombinant Proteins/metabolism
MH  - Rhinitis, Allergic, Perennial/epidemiology/immunology
MH  - Skin Tests
MH  - Tropomyosin/metabolism
MH  - Young Adult
EDAT- 2009/04/03 09:00
MHDA- 2011/07/29 06:00
CRDT- 2009/04/03 09:00
PHST- 2009/04/03 09:00 [entrez]
PHST- 2009/04/03 09:00 [pubmed]
PHST- 2011/07/29 06:00 [medline]
AID - kqp041 [pii]
AID - 10.1093/occmed/kqp041 [doi]
PST - ppublish
SO  - Occup Med (Lond). 2009 Jun;59(4):243-8. doi: 10.1093/occmed/kqp041. Epub 2009 Apr 
      1.