PMID- 1934448
OWN - NLM
STAT- MEDLINE
DCOM- 19911216
LR  - 20121115
IS  - 0009-7322 (Print)
IS  - 0009-7322 (Linking)
VI  - 84
IP  - 5 Suppl
DP  - 1991 Nov
TI  - Aortic valve replacement with pulmonary or aortic allografts.
PG  - III89-93
AB  - Limited availability of aortic valve allografts suggests consideration of 
      pulmonary valve allografts for aortic valve replacement (AVR). From 1987 through 
      1990, 20 patients underwent AVR with cryopreserved aortic allografts (group 1). 
      Five patients underwent AVR with pulmonary allografts (group 2) because no aortic 
      allografts of the appropriate size were available. Indications for AVR in group 1 
      were endocarditis in five patients, aortic insufficiency in six, and aortic 
      stenosis in nine. Indications for AVR in group 2 were endocarditis in two 
      patients and aortic insufficiency in three. In group 1 there was one operative 
      death and two late deaths resulting from noncardiac causes. There were no 
      operative or late deaths in group 2. Follow-up was complete (group 1: 1-32 months 
      [mean, 14 months]; group 2: 1-24 months [mean, 13 months]). All surviving 
      patients remain in New York Heart Association (NYHA) class I or II. Postoperative 
      catheterization was performed in 21 of 24 surviving patients. All patients have 
      been followed since hospitalization with serial studies that included 
      computerized cine tomography of the chest and echocardiograms. No false 
      aneurysms, stenoses, or clinically significant regurgitation have occurred, 
      although one patient in group 2 showed 2+ insufficiency at catheterization. One 
      group 1 patient required repeat AVR for recurrent endocarditis. There were no 
      reoperations in group 2. Although longer-term follow-up with larger numbers of 
      patients is necessary, it seems that operative and early postoperative results 
      for AVR have been similar with aortic and pulmonary valve allografts. In selected 
      patients AVR with pulmonary allografts may be appropriate to consider when 
      properly sized aortic allografts are unavailable.
FAU - Lupinetti, F M
AU  - Lupinetti FM
AD  - Division of Cardiothoracic Surgery, University of Iowa School of Medicine, Iowa 
      City.
FAU - Lemmer, J H Jr
AU  - Lemmer JH Jr
FAU - Ferguson, D W
AU  - Ferguson DW
FAU - Stanford, W
AU  - Stanford W
FAU - Behrendt, D M
AU  - Behrendt DM
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Circulation
JT  - Circulation
JID - 0147763
SB  - IM
MH  - Adult
MH  - Aortic Valve/*transplantation
MH  - Aortic Valve Insufficiency/*surgery
MH  - Aortic Valve Stenosis/*surgery
MH  - Cardiac Catheterization
MH  - Cryopreservation
MH  - Endocarditis/*surgery
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Postoperative Complications/epidemiology
MH  - Pulmonary Valve/*transplantation
MH  - Time Factors
MH  - Transplantation, Homologous
EDAT- 1991/11/11 19:15
MHDA- 2001/03/28 10:01
CRDT- 1991/11/11 19:15
PHST- 1991/11/11 19:15 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1991/11/11 19:15 [entrez]
PST - ppublish
SO  - Circulation. 1991 Nov;84(5 Suppl):III89-93.