PMID- 1936162
OWN - NLM
STAT- MEDLINE
DCOM- 19911129
LR  - 20190516
IS  - 0950-2688 (Print)
IS  - 0950-2688 (Linking)
VI  - 107
IP  - 2
DP  - 1991 Oct
TI  - A serosurvey for HTLV-I among high-risk populations and normal adults in Egypt.
PG  - 429-33
AB  - The prevalence of antibodies to human T-cell lymphotropic virus type I (HTLV-I) 
      was determined in high-risk groups and normal adults in Egypt. Among 647 
      individuals tested, 6 (0.9%) were confirmed positive by western blot analysis. 
      These included 2 (0.7%) of 279 drug addicts, 1 (3.3%) of 30 patients with 
      sexually transmitted diseases, and 3 (2.2%) of 133 healthy individuals. Antibody 
      was not detected in 47 blood recipients or 158 prostitutes. There was no 
      correlation between sex or geographical location and HTLV-I infection. 
      Fifty-three of the 647 sera (8%) were initially reactive by ELISA, but only 12 
      sera were repeatedly reactive. Since only 4 of these repeatedly reactive sera 
      were confirmed by the western blot, the frequency of false positives using the 
      DuPont screening ELISA was 1.2% (8/643). Two additional sera, confirmed positive 
      by western blot, had been reactive, but not repeatedly, by ELISA. In comparison 
      to the prevalence of HTLV-I antibody among risk groups in many parts of the 
      world, the prevalence in Egypt was low.
FAU - Constantine, N T
AU  - Constantine NT
AD  - U.S. Naval Medical Research Unit No. 3, Cairo, Egypt.
FAU - Fathi Sheba, M
AU  - Fathi Sheba M
FAU - Corwin, A L
AU  - Corwin AL
FAU - Danahy, R S
AU  - Danahy RS
FAU - Callahan, J D
AU  - Callahan JD
FAU - Watts, D M
AU  - Watts DM
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - England
TA  - Epidemiol Infect
JT  - Epidemiology and infection
JID - 8703737
RN  - 0 (HTLV-I Antibodies)
RN  - 9001-27-8 (Factor VIII)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Blood Donors
MH  - Blood Transfusion
MH  - Blotting, Western
MH  - Egypt/epidemiology
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Factor VIII/administration & dosage
MH  - Female
MH  - HTLV-I Antibodies/*blood
MH  - HTLV-I Infections/*epidemiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Risk Factors
MH  - Sex Work
MH  - Sexually Transmitted Diseases/complications
MH  - Substance-Related Disorders/complications
PMC - PMC2272073
EDAT- 1991/10/01 00:00
MHDA- 1991/10/01 00:01
PMCR- 1992/10/01
CRDT- 1991/10/01 00:00
PHST- 1991/10/01 00:00 [pubmed]
PHST- 1991/10/01 00:01 [medline]
PHST- 1991/10/01 00:00 [entrez]
PHST- 1992/10/01 00:00 [pmc-release]
AID - 10.1017/s0950268800049074 [doi]
PST - ppublish
SO  - Epidemiol Infect. 1991 Oct;107(2):429-33. doi: 10.1017/s0950268800049074.