PMID- 19362318
OWN - NLM
STAT- MEDLINE
DCOM- 20090903
LR  - 20091111
IS  - 1532-8430 (Electronic)
IS  - 0022-0736 (Linking)
VI  - 42
IP  - 4
DP  - 2009 Jul-Aug
TI  - Predictive value of Q waves on the 12-lead electrocardiogram after reperfusion 
      therapy for ST elevation myocardial infarction.
PG  - 310-8
LID - 10.1016/j.jelectrocard.2009.03.008 [doi]
AB  - DESIGN: The data used for the present study were obtained as part of a clinical 
      trial evaluating the effect of thrombus aspiration after primary percutaneous 
      coronary intervention (PCI). SETTING: The study was conducted at a tertiary 
      referral facility for primary PCI at a University Medical Center Groningen in The 
      Netherlands. BACKGROUND: Prognosis after ST elevation myocardial infarction 
      (STEMI) is strongly related to infarct size. METHODS: As part of a randomized 
      clinical trial, the first electrocardiogram (ECG) after primary PCI for STEMI was 
      analyzed for the incidence of Q waves (>0.1 mV) on the 12-lead ECG. Infarct size 
      was measured as area under curve (AUC) of creatine kinase (CK) and CK-myocardial 
      band (CK-MB). RESULTS AND CONCLUSION: Nine hundred thirty-three patients were 
      included, the median number of Q waves on the postprocedural ECG was 3 
      (interquartile range, 1-4). The number of Q waves on the postprocedural ECG was 
      an independent predictor of infarct size measured either as AUC of CK (P < .001) 
      or AUC of CK-MB (P < .001) and was a significant predictor of mortality during 
      follow-up of 14 months. In conclusion, the number of Q waves on the 
      postprocedural 12-lead ECG after primary PCI for STEMI is a strong predictor of 
      infarct size and long-term mortality.
FAU - van der Vleuten, Pieter A
AU  - van der Vleuten PA
AD  - Thoraxcenter, Department of Cardiology, University Medical Center Groningen, 
      University of Groningen, Groningen, The Netherlands. 
      p.a.van.der.vleuten@thorax.umcg.nl
FAU - Vogelzang, Mathijs
AU  - Vogelzang M
FAU - Svilaas, Tone
AU  - Svilaas T
FAU - van der Horst, Iwan C C
AU  - van der Horst IC
FAU - Tio, Rene A
AU  - Tio RA
FAU - Zijlstra, Felix
AU  - Zijlstra F
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20090410
PL  - United States
TA  - J Electrocardiol
JT  - Journal of electrocardiology
JID - 0153605
SB  - IM
MH  - Electrocardiography/*methods
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*diagnosis/*therapy
MH  - Myocardial Reperfusion/*methods
MH  - Prognosis
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Treatment Outcome
EDAT- 2009/04/14 09:00
MHDA- 2009/09/04 06:00
CRDT- 2009/04/14 09:00
PHST- 2008/10/28 00:00 [received]
PHST- 2009/04/14 09:00 [entrez]
PHST- 2009/04/14 09:00 [pubmed]
PHST- 2009/09/04 06:00 [medline]
AID - S0022-0736(09)00064-8 [pii]
AID - 10.1016/j.jelectrocard.2009.03.008 [doi]
PST - ppublish
SO  - J Electrocardiol. 2009 Jul-Aug;42(4):310-8. doi: 
      10.1016/j.jelectrocard.2009.03.008. Epub 2009 Apr 10.