PMID- 19369877
OWN - NLM
STAT- MEDLINE
DCOM- 20090924
LR  - 20161125
IS  - 1741-8275 (Electronic)
IS  - 1741-8267 (Linking)
VI  - 16
IP  - 3
DP  - 2009 Jun
TI  - Regional differences in the prevalence of left ventricular hypertrophy within 
      Germany.
PG  - 392-400
LID - 10.1097/HJR.0b013e32832a4dc1 [doi]
AB  - BACKGROUND: There are considerable regional disparities in the prevalence of 
      cardiovascular risk factors within Germany. We undertook this study to 
      investigate differences in the prevalence of left ventricular hypertrophy (LVH) 
      between northeast and southwest Germany. METHODS: Data from two population-based 
      studies, Kooperative Gesundheitsforschung im Raum Augsburg (KORA) conducted in 
      southwest and Study of Health in Pomerania (SHIP) conducted in northeast Germany, 
      were utilized. The study population comprised 2,516 women and men (835 from KORA 
      and 1,681 from SHIP) aged 45-74 years who had no history of myocardial 
      infarction. Echocardiograms were obtained according to standard protocols. Left 
      ventricular mass (LVM), left ventricular mass indexed for body height, and left 
      ventricular hypertrophy were used as dependent variables in multivariable 
      analyses. RESULTS: SHIP participants had higher LVM and left ventricular mass 
      index values compared with KORA participants. These differences remained after 
      analyses were adjusted for major confounders including obesity and hypertension. 
      Consequently, there were higher proportions of LVH in SHIP compared with KORA 
      across all 10-year age groups. Multivariable logistic regression revealed that 
      the odds for LVH in participants living in northeast Germany were higher in women 
      and men, respectively, by 1.57 (95% confidence interval: 1.18-2.09) and 1.68 (95% 
      confidence interval: 1.25-2.27) than in participants living in southwest Germany. 
      Potential methodological differences between studies do not seem to account for 
      these findings. CONCLUSION: There is a higher prevalence of LVH in northeast 
      compared with southwest Germany. Regional disparities in hypertension and 
      overweight only partly explain this difference.
FAU - Volzke, Henry
AU  - Volzke H
AD  - Institute for Community Medicine, Ernst Moritz Arndt University, Greifswald, 
      Germany. voelzke@uni-greifswald.de
FAU - Stritzke, Jan
AU  - Stritzke J
FAU - Kuch, Bernhard
AU  - Kuch B
FAU - Schmidt, Carsten O
AU  - Schmidt CO
FAU - Ludemann, Jan
AU  - Ludemann J
FAU - Doring, Angela
AU  - Doring A
FAU - Schunkert, Heribert
AU  - Schunkert H
FAU - Hense, Hans-Werner
AU  - Hense HW
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Eur J Cardiovasc Prev Rehabil
JT  - European journal of cardiovascular prevention and rehabilitation : official 
      journal of the European Society of Cardiology, Working Groups on Epidemiology & 
      Prevention and Cardiac Rehabilitation and Exercise Physiology
JID - 101192000
SB  - IM
MH  - Aged
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus/epidemiology
MH  - Female
MH  - Germany/epidemiology
MH  - *Health Status Disparities
MH  - Humans
MH  - Hypertension/complications/epidemiology
MH  - Hypertrophy, Left Ventricular/diagnostic imaging/*epidemiology/etiology
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Obesity/complications/epidemiology
MH  - Odds Ratio
MH  - Population Surveillance
MH  - Prevalence
MH  - *Residence Characteristics
MH  - Risk Assessment
MH  - Risk Factors
MH  - Smoking/adverse effects/epidemiology
MH  - Ultrasonography
EDAT- 2009/04/17 09:00
MHDA- 2009/09/25 06:00
CRDT- 2009/04/17 09:00
PHST- 2009/04/17 09:00 [entrez]
PHST- 2009/04/17 09:00 [pubmed]
PHST- 2009/09/25 06:00 [medline]
AID - 10.1097/HJR.0b013e32832a4dc1 [doi]
PST - ppublish
SO  - Eur J Cardiovasc Prev Rehabil. 2009 Jun;16(3):392-400. doi: 
      10.1097/HJR.0b013e32832a4dc1.